{"id":"W2888458270","doi":"10.1016/s0140-6736(18)31858-0","title":"Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial","year":2018,"lang":"en","type":"article","venue":"The Lancet","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":785,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Servier; Abbott Vascular; Regeneron Pharmaceuticals; Daiichi Sankyo Europe; Sanofi; University of Bern; Amarin Corporation; Boston Scientific Corporation; Amgen; Pfizer; Biosensors International Group; Canada Research Chairs; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Ticagrelor; Medicine; Aspirin; Clopidogrel; Percutaneous coronary intervention; Acute coronary syndrome; Coronary artery disease; Myocardial infarction; Internal medicine; Clinical endpoint; Cardiology; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002232335,0.002121804,0.004044551,0.0004372219,0.0005337014,0.001527106,0.001154824,0.002690743,0.009066314],"category_scores_gemma":[0.002967831,0.0009092072,0.003649468,0.0005897796,0.001058,0.00157252,0.0005990604,0.004081686,0.001575204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000889423,"about_ca_system_score_gemma":0.001060197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001515426,"about_ca_topic_score_gemma":0.003711884,"domain_scores_codex":[0.9989765,0.0004623424,0.000102404,0.000228787,0.00007036892,0.0001596381],"domain_scores_gemma":[0.9984745,0.0005669185,0.0003508936,0.0001608832,0.00007266571,0.0003741743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9922419,0.001124075,0.0002196077,0.0004316691,0.001126777,0.00002526644,0.00002722761,0.00007850985,0.0008717844,0.00005127882,0.0003349601,0.003467029],"study_design_scores_gemma":[0.9812878,0.01524573,0.001468008,0.00004005857,0.001248939,0.000034596,0.00002057381,0.0001526195,0.0001249516,0.0001072835,0.0002552325,0.00001408314],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770778,0.01358791,0.0006113898,0.001786396,0.001657716,0.001239893,0.001447706,0.0001208898,0.00247023],"genre_scores_gemma":[0.9831518,0.005366339,0.001611965,0.001765655,0.001664619,0.00106856,0.001409092,0.00003922794,0.003922751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009066314,"threshold_uncertainty_score":0.03032982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04259067970504685,"score_gpt":0.324734246856156,"score_spread":0.2821435671511091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}