{"id":"W2888461788","doi":"10.1186/s12864-018-5000-7","title":"Murine host response to Neisseria gonorrhoeae upper genital tract infection reveals a common transcriptional signature, plus distinct inflammatory responses that vary between reproductive cycle phases","year":2018,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; School of Medicine, Boston University","keywords":"Neisseria gonorrhoeae; Biology; Chemokine; Immunology; Estrous cycle; Innate immune system; Immune system; Microbiology; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001760695,0.0003388265,0.000220238,0.0005737375,0.0001766733,0.0002255445,0.0001820775,0.0003056032,0.001733569],"category_scores_gemma":[0.0001263266,0.0002068889,0.0002947924,0.0001817055,0.0002953511,0.0001133917,0.0002069694,0.0006708695,0.0003751397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003263042,"about_ca_system_score_gemma":0.0001926088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004834939,"about_ca_topic_score_gemma":0.0008797189,"domain_scores_codex":[0.9997625,0.0000364656,0.00001681156,0.000070966,0.00004564599,0.00006759423],"domain_scores_gemma":[0.999843,0.00003062845,0.0000443135,0.00002055574,0.00001410645,0.00004740323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003718614,0.0001012217,0.001219664,0.00002810559,0.000004847476,0.00002915834,0.00003745595,0.0000829428,0.9970648,0.00007553483,0.00004175183,0.000942544],"study_design_scores_gemma":[0.00007032611,0.003816295,0.06833002,0.00003615717,0.00004844509,0.000590383,0.0001744247,0.002259965,0.9216414,0.0001934609,0.002822432,0.00001665927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995685,0.0006307323,0.001608636,0.00006124743,0.00001180586,0.0000434834,0.001150861,0.00006102378,0.0007472637],"genre_scores_gemma":[0.9901258,0.0006057647,0.003284736,0.0001287275,0.000009150909,0.0001946102,0.002383528,0.00003285748,0.003234788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001733569,"threshold_uncertainty_score":0.005799353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02886877487721354,"score_gpt":0.2777055666748551,"score_spread":0.2488367917976415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}