{"id":"W2888628330","doi":"10.1056/nejmoa1808721","title":"Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients","year":2018,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Pharmacology and Obesity Treatment","field":"Medicine","cited_by":264,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; McMaster University","funders":"Eisai","keywords":"Medicine; Internal medicine; Myocardial infarction; Hazard ratio; Overweight; Odds ratio; Placebo; Glycemic; Cardiology; Confidence interval; Obesity; Insulin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001436551,0.0001463481,0.0005488435,0.0001335735,0.0001523331,0.0002903969,0.0001192918,0.0003311138,0.001205581],"category_scores_gemma":[0.002955817,0.00006159436,0.0004243208,0.0001442761,0.0002146651,0.0001438761,0.0001467021,0.0006236884,0.0001383108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001874359,"about_ca_system_score_gemma":0.0002167729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001462329,"about_ca_topic_score_gemma":0.00019548,"domain_scores_codex":[0.9994925,0.0003082531,0.00004194911,0.00003569276,0.00008197282,0.00003964075],"domain_scores_gemma":[0.9981456,0.0007133818,0.0007931024,0.00006483186,0.00009954798,0.0001835769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4235827,0.003076159,0.1840987,0.002258795,0.002098359,0.001140082,0.0002500731,0.001690495,0.03441575,0.0003718461,0.002971637,0.3440455],"study_design_scores_gemma":[0.07803029,0.2385076,0.6364597,0.0006696573,0.004007537,0.005144596,0.0002645943,0.005454217,0.01911719,0.001160011,0.01111603,0.00006852704],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889791,0.008489747,0.0003122929,0.0004575439,0.00004487064,0.00009096697,0.0001242872,0.00001423523,0.00148692],"genre_scores_gemma":[0.9977239,0.001469529,0.0001649744,0.0002290283,0.0001045351,0.00004966931,0.0001227205,0.000001627614,0.0001340782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436551,"threshold_uncertainty_score":0.007597268,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01865751148934344,"score_gpt":0.2945313791452912,"score_spread":0.2758738676559478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}