{"id":"W2888639317","doi":"10.1172/jci.insight.122204","title":"Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma","year":2018,"lang":"en","type":"article","venue":"JCI Insight","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Health Research Council of New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery; Cancer Research Trust New Zealand; Cancer Society of New Zealand; Halozyme; University of Auckland; Novocure; Genentech; Institute of Environmental Science and Research; Celgene; AstraZeneca; Pfizer","keywords":"Human papillomavirus; Head and neck squamous-cell carcinoma; Head and neck; Basal cell; Oncology; Medicine; Internal medicine; Cancer research; Head and neck cancer; Cancer; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001262643,0.0001754061,0.0002861903,0.0001788292,0.0001564696,0.0001837438,0.0001183654,0.000190354,0.001234101],"category_scores_gemma":[0.00007122674,0.00006537986,0.0002213752,0.0001022102,0.0001451905,0.0001119591,0.0001653727,0.0002980798,0.0001801264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004958156,"about_ca_system_score_gemma":0.0002909484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008226532,"about_ca_topic_score_gemma":0.002572388,"domain_scores_codex":[0.9999503,0.000007957238,0.000002826109,0.000009807995,0.00001585968,0.00001317356],"domain_scores_gemma":[0.9999723,0.000005380847,0.00000533309,0.000003054078,0.000004836391,0.000009005123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001892631,0.0003638563,0.003648239,0.0002657639,0.00005617859,0.0004086295,0.0001020272,0.001258767,0.8626512,0.000494461,0.001217186,0.127641],"study_design_scores_gemma":[0.0008056264,0.01236198,0.03646071,0.00009467867,0.000149552,0.00665131,0.0001425268,0.002827835,0.8807636,0.0005159009,0.05919506,0.00003123178],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834266,0.008945677,0.002518044,0.0002859441,0.00005817536,0.000208564,0.0003716052,0.0001115202,0.004073867],"genre_scores_gemma":[0.9928347,0.003240372,0.00148677,0.00009622413,0.00001194658,0.00006524993,0.0004775533,0.00001655731,0.001770598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234101,"threshold_uncertainty_score":0.004128516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04744462273270051,"score_gpt":0.3223991180531172,"score_spread":0.2749544953204167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}