{"id":"W2888779673","doi":"10.1186/s13395-018-0173-y","title":"Biochemical and pathological changes result from mutated Caveolin-3 in muscle","year":2018,"lang":"en","type":"article","venue":"Skeletal Muscle","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital; Children's Hospital of Eastern Ontario; McGill University; Jewish General Hospital","funders":"Deutsche Gesellschaft für Muskelkranke; Bundesministerium für Bildung und Forschung; National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Golgi apparatus; Cell biology; Endoplasmic reticulum; Biology; Proteostasis; Cytoskeleton; Proteomics; Immunoprecipitation; Dystroglycan; Caveolin 3; Sarcolemma; Extracellular matrix; Laminin; Caveolae; Myocyte; Biochemistry; Signal transduction; Gene; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001327505,0.0001745484,0.0001677096,0.00004365485,0.00006136078,0.00002589773,0.0001499115,0.0002525889,0.00007224282],"category_scores_gemma":[0.0001419936,0.0001578532,0.00004590843,0.0001314533,0.0003169299,0.000004122054,0.0001463724,0.0001248158,0.00003000073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000902896,"about_ca_system_score_gemma":0.00002930699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001427544,"about_ca_topic_score_gemma":0.0003746139,"domain_scores_codex":[0.998831,0.00004494528,0.0001798142,0.0005252188,0.0001078941,0.000311125],"domain_scores_gemma":[0.9994982,0.00001714098,0.00004927481,0.0002621358,0.00006678724,0.0001064274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003948717,0.00007068219,0.0005536955,0.00001092404,0.000008532865,0.00002670912,0.0001146423,2.903974e-7,0.9877217,0.00001822593,0.0004131918,0.01102191],"study_design_scores_gemma":[0.001227607,0.0005194239,0.066794,0.00002936349,0.00001694395,0.00001826577,0.0002071757,0.00006323763,0.8868194,0.0005765004,0.04333136,0.0003967657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964561,0.001641609,0.00008864985,0.0002665244,0.0001198821,0.000116927,0.00005626143,0.00002492651,0.001229145],"genre_scores_gemma":[0.9979312,0.0002588496,0.0003149799,0.0004018217,0.0005958881,0.00001758354,0.0002518798,0.00002075113,0.000206985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1009024,"threshold_uncertainty_score":0.6437066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000778741626523,"score_gpt":0.2390119213170274,"score_spread":0.2290041339007622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}