{"id":"W2888779673","doi":"10.1186/s13395-018-0173-y","title":"Biochemical and pathological changes result from mutated Caveolin-3 in muscle","year":2018,"lang":"en","type":"article","venue":"Skeletal Muscle","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital; Children's Hospital of Eastern Ontario; McGill University; Jewish General Hospital","funders":"Deutsche Gesellschaft für Muskelkranke; Bundesministerium für Bildung und Forschung; National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Golgi apparatus; Cell biology; Endoplasmic reticulum; Biology; Proteostasis; Cytoskeleton; Proteomics; Immunoprecipitation; Dystroglycan; Caveolin 3; Sarcolemma; Extracellular matrix; Laminin; Caveolae; Myocyte; Biochemistry; Signal transduction; Gene; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001670567,0.0004909475,0.0002288348,0.0005208597,0.0001907278,0.000194386,0.0002635598,0.0006379535,0.0008585873],"category_scores_gemma":[0.0001942383,0.0001898511,0.0004497418,0.0002687305,0.0003599528,0.0001857898,0.0002842571,0.0003836888,0.0002827551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003081891,"about_ca_system_score_gemma":0.000149456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000521887,"about_ca_topic_score_gemma":0.0004119325,"domain_scores_codex":[0.9998696,0.00001181335,0.00002117259,0.00003940899,0.00003656999,0.000021354],"domain_scores_gemma":[0.99983,0.00002548721,0.00007378887,0.00001410163,0.00002234802,0.0000341567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002735375,0.00004988006,0.003374711,0.00007698744,0.00003227447,0.003932129,0.00002889188,0.00008451345,0.9909218,0.00005938166,0.00007809779,0.001087795],"study_design_scores_gemma":[0.00006479085,0.001308689,0.1325577,0.00003873482,0.0002626395,0.05385199,0.0001339433,0.00253021,0.8063968,0.0003122835,0.002514166,0.00002799327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977264,0.0007202898,0.0008734095,0.00006252644,0.00002241178,0.00001760648,0.0002290532,0.00006949752,0.0002788841],"genre_scores_gemma":[0.9967505,0.0004625244,0.001377412,0.0000787169,0.00001250451,0.00002691933,0.0005210149,0.0000225201,0.0007480384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008585873,"threshold_uncertainty_score":0.002872229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000778741626523,"score_gpt":0.2390119213170274,"score_spread":0.2290041339007622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}