{"id":"W2888826137","doi":"10.1371/journal.pone.0202997","title":"Mucosal antibody responses to vaccines targeting SIV protease cleavage sites or full-length Gag and Env proteins in Mauritian cynomolgus macaques","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Virology; Antibody; Group-specific antigen; Simian immunodeficiency virus; Vaccine trial; HIV vaccine; Lentivirus; Biology; Western blot; Macaque; Immunity; Immunology; Neutralizing antibody; AIDS Vaccines; Vaccination; Immune system; Virus; Viral disease; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002191861,0.00022997,0.0002315027,0.0002614175,0.0001710557,0.000216227,0.0001394066,0.0003871311,0.001205711],"category_scores_gemma":[0.0003334011,0.0001472834,0.000181296,0.00007584463,0.0002675333,0.0001654285,0.000162264,0.0007279931,0.0001498747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002342113,"about_ca_system_score_gemma":0.0001576212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001170477,"about_ca_topic_score_gemma":0.001783618,"domain_scores_codex":[0.9998604,0.00003215451,0.000008343089,0.00002485125,0.00002549679,0.00004866418],"domain_scores_gemma":[0.9998727,0.00002897983,0.00002480184,0.00001362095,0.00001773675,0.00004210774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001151604,0.0003681361,0.002327927,0.00006881027,0.00001536397,0.00009169739,0.0001437531,0.00004486289,0.9914371,0.00003378201,0.00005272421,0.004264223],"study_design_scores_gemma":[0.0004051837,0.04475332,0.2177874,0.00005638145,0.0001769561,0.00118738,0.0005308165,0.001372667,0.7302269,0.0001525155,0.003335222,0.00001531241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999506,0.0002176407,0.00006390191,0.00002260904,0.000005953447,0.00001005784,0.00001416449,0.000005076698,0.0001546368],"genre_scores_gemma":[0.9984902,0.0002133788,0.0002166597,0.0000425503,0.00001025814,0.00003220281,0.00007332665,0.000002990527,0.0009184864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001205711,"threshold_uncertainty_score":0.004033506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03587366517973376,"score_gpt":0.2929041059296305,"score_spread":0.2570304407498967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}