{"id":"W2888862173","doi":"10.1038/s41467-018-05806-0","title":"Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Health Canada; Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"Sydney Medical School; Canadian Institutes of Health Research; National Institutes of Health; Cardiac Society of Australia and New Zealand; Diabetes Australia; Canadian Blood Services; National Heart Foundation of Australia; Royal College of Pathologists of Australasia; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Integrin; Platelet; Hemostasis; Platelet activation; Chemistry; Apolipoprotein B; Postprandial; Internal medicine; Biochemistry; Cell biology; Endocrinology; Pharmacology; Medicine; Receptor; Biology; Cholesterol; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001289414,0.0001839674,0.000163873,0.0001476852,0.0001287975,0.000281157,0.0001716157,0.0002184076,0.001359183],"category_scores_gemma":[0.0002062639,0.00008297591,0.0002010318,0.0001228387,0.0001248537,0.00007555833,0.0001341023,0.0003463961,0.0004386452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153285,"about_ca_system_score_gemma":0.00022119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007577777,"about_ca_topic_score_gemma":0.0008233673,"domain_scores_codex":[0.9998498,0.00004494975,0.00001305943,0.00001642763,0.00003706189,0.00003862016],"domain_scores_gemma":[0.9999312,0.00001276571,0.00001798984,0.000008213055,0.000008563044,0.00002115949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002986042,0.00009484613,0.0006790476,0.0000442004,0.00002345915,0.00005940178,0.00001103515,0.00007685497,0.9898085,0.000133737,0.0004244341,0.008345736],"study_design_scores_gemma":[0.0001687568,0.001694352,0.026225,0.00001983966,0.00004951415,0.0008284376,0.00004047236,0.001885996,0.9581934,0.0002427825,0.010644,0.000007609261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818507,0.009412712,0.002856634,0.0004549674,0.0001114447,0.00002825678,0.0001264736,0.0001270822,0.005031772],"genre_scores_gemma":[0.9936771,0.002021758,0.001454881,0.000134048,0.00004210571,0.00001923008,0.0001706327,0.00001454367,0.002465813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001359183,"threshold_uncertainty_score":0.00454694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02901579675082187,"score_gpt":0.3373725731185061,"score_spread":0.3083567763676842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}