{"id":"W2888862173","doi":"10.1038/s41467-018-05806-0","title":"Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Health Canada; Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"Sydney Medical School; Canadian Institutes of Health Research; National Institutes of Health; Cardiac Society of Australia and New Zealand; Diabetes Australia; Canadian Blood Services; National Heart Foundation of Australia; Royal College of Pathologists of Australasia; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Integrin; Platelet; Hemostasis; Platelet activation; Chemistry; Apolipoprotein B; Postprandial; Internal medicine; Biochemistry; Cell biology; Endocrinology; Pharmacology; Medicine; Receptor; Biology; Cholesterol; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008619036,0.0001181462,0.0001956914,0.0001009085,0.0002512569,0.00002140485,0.0002268871,0.0002441374,0.00005565396],"category_scores_gemma":[0.0001160866,0.00009422848,0.00004269499,0.0002663115,0.0002766407,0.00007158042,0.0002182751,0.0006007932,0.00008373645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003871702,"about_ca_system_score_gemma":0.00004623053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001101694,"about_ca_topic_score_gemma":0.0008218787,"domain_scores_codex":[0.9993964,0.00003822553,0.0001385642,0.0001606376,0.000114886,0.0001513071],"domain_scores_gemma":[0.9985509,0.00006312409,0.00004811667,0.001103905,0.000139787,0.00009415294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000524747,0.007999512,0.3424421,0.0002577678,0.002976648,0.00007305889,0.01006181,2.83061e-7,0.06786372,0.1597484,0.131978,0.276074],"study_design_scores_gemma":[0.006888622,0.001288924,0.4381202,0.0006119957,0.0006582606,0.0003930757,0.0008809403,0.0007213566,0.02303627,0.005456976,0.5211991,0.000744327],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.94239,0.006045616,0.00001560494,0.01512561,0.00007502361,0.0004227154,0.0000254097,0.00009821712,0.03580184],"genre_scores_gemma":[0.9922958,0.001097064,0.004874476,0.001097165,0.00005174653,0.00003997705,0.0001029323,0.00001642402,0.0004243865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3892211,"threshold_uncertainty_score":0.3842526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02901579675082187,"score_gpt":0.3373725731185061,"score_spread":0.3083567763676842,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}