{"id":"W2888873669","doi":"10.1007/s11095-018-2469-3","title":"Orcinol Glucoside Loaded Polymer - Lipid Hybrid Nanostructured Lipid Carriers: Potential Cytotoxic Agents against Gastric, Colon and Hepatoma Carcinoma Cell Lines","year":2018,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Science and Engineering Research Board; University Grants Commission","keywords":"Zeta potential; Polyethylene glycol; Differential scanning calorimetry; Chemistry; PEG ratio; In vivo; Cytotoxicity; Stearate; Crystallinity; Biophysics; In vitro; Nuclear chemistry; Materials science; Biochemistry; Nanoparticle; Nanotechnology; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007437288,0.0002197111,0.0001479801,0.0001224962,0.00008545636,0.0001897183,0.0001194366,0.0002727765,0.0008405861],"category_scores_gemma":[0.00009445594,0.0000878498,0.0001230926,0.0001249623,0.0001098348,0.0002627258,0.0001421151,0.0002253009,0.0001773598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001581947,"about_ca_system_score_gemma":0.0001511964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005275916,"about_ca_topic_score_gemma":0.0009103466,"domain_scores_codex":[0.999959,0.0000068944,0.000002712641,0.00001018895,0.00001005141,0.0000111385],"domain_scores_gemma":[0.9999633,0.000007620391,0.000009861255,0.00000281348,0.000009138837,0.00000716612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001034812,0.00001669141,0.00006276878,0.00003584943,0.000002724836,0.00004664598,0.00001267996,0.0001039247,0.9972928,0.00008568126,0.00003115125,0.002205566],"study_design_scores_gemma":[0.0000125461,0.0003698538,0.0006514846,0.000004164957,0.00001933879,0.00008832248,0.0000151963,0.0006844143,0.9964309,0.0000181905,0.001701145,0.000004359691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941903,0.001312501,0.002493707,0.00007372765,0.00002455425,0.00002527177,0.00008478494,0.00005404648,0.001741152],"genre_scores_gemma":[0.9944238,0.000932857,0.001811578,0.00003476496,0.000005840746,0.00001820941,0.00008562948,0.000009686657,0.002677724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008405861,"threshold_uncertainty_score":0.002812028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1524510561137227,"score_gpt":0.4617857196646298,"score_spread":0.3093346635509071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}