{"id":"W2888900018","doi":"10.1007/978-1-4939-8651-4_28","title":"Systemic and ICV Injections of Antisense Oligos into SMA Mice and Evaluation","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Muscular Dystrophy Canada; University of Alberta","funders":"Canadian Institutes of Health Research; Ministry of Education, India; Ministry of Earth Sciences","keywords":"SMA*; Chemistry; Pharmacology; Biology; Computer science; Algorithm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006960389,0.001422767,0.0005736111,0.001623626,0.0004537308,0.000417802,0.0005477374,0.001115621,0.003438612],"category_scores_gemma":[0.0002497178,0.0003967393,0.0006236929,0.0004446121,0.0008880465,0.0006029475,0.0002454769,0.002176464,0.0009063981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004973988,"about_ca_system_score_gemma":0.0007335491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001473455,"about_ca_topic_score_gemma":0.003433656,"domain_scores_codex":[0.9994167,0.00006049991,0.00004096312,0.0001713127,0.0001175307,0.0001930275],"domain_scores_gemma":[0.9996062,0.00006822737,0.00009871135,0.00004757867,0.00006851177,0.0001108429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008209292,0.0003271696,0.0002518363,0.00006660439,0.00001414394,0.00005593498,0.00004260544,0.0001655294,0.9944312,0.0003859475,0.0001957431,0.00324237],"study_design_scores_gemma":[0.0001275417,0.003157481,0.002367808,0.00001582417,0.00007062467,0.0001778582,0.00005514694,0.001088171,0.9901367,0.0001529846,0.002635068,0.00001477531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9124522,0.003913837,0.05505902,0.0005404457,0.0006547793,0.001747828,0.009242054,0.001835592,0.01455434],"genre_scores_gemma":[0.9101638,0.004757991,0.03757553,0.0003714765,0.0001853533,0.002798411,0.006188085,0.0005050789,0.03745437],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.003438612,"threshold_uncertainty_score":0.01150334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03997114412849086,"score_gpt":0.4808754055578225,"score_spread":0.4409042614293316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}