{"id":"W2888902889","doi":"10.3389/fncel.2018.00278","title":"Contributions of the Hippocampal CA3 Circuitry to Acute Seizures and Hyperexcitability Responses in Mouse Models of Brain Ischemia","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"","keywords":"Hippocampal formation; Neuroscience; Dentate gyrus; Hippocampus; Excitatory postsynaptic potential; Perforant path; Postsynaptic potential; Medicine; Entorhinal cortex; Ischemia; Inhibitory postsynaptic potential; Anesthesia; Psychology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001085637,0.0002009543,0.0003638925,0.0004465937,0.0002558051,0.00003707837,0.001352777,0.0000913269,0.000004949651],"category_scores_gemma":[0.004294361,0.0001655645,0.00007186988,0.002431756,0.003744811,0.0003891823,0.000609294,0.0004659612,0.00000139333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006278434,"about_ca_system_score_gemma":0.0003110351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003294928,"about_ca_topic_score_gemma":0.00000890194,"domain_scores_codex":[0.9962974,0.0008980242,0.0005052755,0.0009635143,0.00066369,0.0006720698],"domain_scores_gemma":[0.9984222,0.0004931075,0.0001493993,0.000658447,0.00009364666,0.0001831806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001982258,0.000142936,0.01309539,0.00001581749,5.629419e-7,0.00004751278,0.0003882685,0.0001692244,0.9852706,0.0001658335,0.0003660697,0.0001395642],"study_design_scores_gemma":[0.0004938713,0.0002576735,0.005230837,0.00001827481,0.00000458761,0.00002925602,0.00005046578,0.009498068,0.9832088,0.0008871129,0.0001821707,0.00013887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955699,0.00003921807,0.001352702,0.001226585,0.0008662138,0.0006921173,0.000137379,0.00001850759,0.00009733662],"genre_scores_gemma":[0.9975641,0.00005394135,0.00009521401,0.001821442,0.00001886402,0.00002662619,1.020743e-7,0.0000146135,0.0004050768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009328844,"threshold_uncertainty_score":0.9989664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03864293179371845,"score_gpt":0.3219316295474249,"score_spread":0.2832886977537064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}