{"id":"W2888906615","doi":"10.1083/jcb.201804137","title":"Macropinosome formation by tent pole ruffling in macrophages","year":2018,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Australian Research Council; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Chinese Academy of Agricultural Sciences; Gordon and Betty Moore Foundation; Australian Cancer Research Foundation; Australian Government; Innovative Research Group Project of the National Natural Science Foundation of China; Howard Hughes Medical Institute","keywords":"Membrane ruffling; Pinocytosis; Innate immune system; Cell biology; Internalization; Biology; Lipopolysaccharide; Immune system; Cell; Immunology; Cytoskeleton; Endocytosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476242,0.000149307,0.000137612,0.0002068551,0.0002811151,0.0003834877,0.0001708552,0.0004745504,0.0005514942],"category_scores_gemma":[0.0001080449,0.0001769045,0.0002007081,0.00008506488,0.000328925,0.0003228924,0.0004151223,0.0004918588,0.0003160191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003658518,"about_ca_system_score_gemma":0.0001806651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003883785,"about_ca_topic_score_gemma":0.000600965,"domain_scores_codex":[0.9998908,0.00001791857,0.000008197809,0.00002145059,0.00003284002,0.00002870308],"domain_scores_gemma":[0.9998816,0.00001590571,0.00004029866,0.00001999286,0.0000125686,0.00002966097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005494058,0.0000108349,0.0004548915,0.00001727854,0.000001865082,0.00008887841,0.0000299883,0.00009615384,0.9978529,0.0004481176,0.00003871862,0.0009053071],"study_design_scores_gemma":[0.00001165665,0.000063542,0.007165942,0.000008652485,0.000005059021,0.0005112638,0.00007549117,0.002523248,0.9869457,0.0003569566,0.002321923,0.00001058361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991468,0.0006844586,0.006411612,0.0001086835,0.00001909935,0.00001306883,0.00009757391,0.0001039741,0.001093557],"genre_scores_gemma":[0.9953458,0.000307401,0.002915982,0.00003242861,0.000004859541,0.00001811923,0.00007153831,0.00001389114,0.001290007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005514942,"threshold_uncertainty_score":0.002654493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005555632800893444,"score_gpt":0.2718285985150837,"score_spread":0.2662729657141903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}