{"id":"W2888906615","doi":"10.1083/jcb.201804137","title":"Macropinosome formation by tent pole ruffling in macrophages","year":2018,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Australian Research Council; National Cancer Institute; National Institutes of Health; Canadian Institutes of Health Research; Chinese Academy of Agricultural Sciences; Gordon and Betty Moore Foundation; Australian Cancer Research Foundation; Australian Government; Innovative Research Group Project of the National Natural Science Foundation of China; Howard Hughes Medical Institute","keywords":"Membrane ruffling; Pinocytosis; Innate immune system; Cell biology; Internalization; Biology; Lipopolysaccharide; Immune system; Cell; Immunology; Cytoskeleton; Endocytosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002955004,0.00008757083,0.0001164399,0.00004848925,0.00004903435,0.00000589111,0.000274442,0.0001024546,0.0000130342],"category_scores_gemma":[0.00003322208,0.00005707982,0.00003932211,0.00006033029,0.0001987497,0.000007091681,0.00007350486,0.0001323605,0.000006267244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000288342,"about_ca_system_score_gemma":0.00003121864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009876805,"about_ca_topic_score_gemma":0.000008769754,"domain_scores_codex":[0.9993055,0.0001078939,0.000283235,0.00007619346,0.00004458373,0.0001825732],"domain_scores_gemma":[0.9994792,0.00001388111,0.0002324942,0.0001438635,0.0001024686,0.00002812578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001121824,0.00002309424,0.0004064279,0.000004268204,0.000004555014,8.642871e-7,0.00007059595,0.000003594479,0.9972823,0.000008798896,0.0007244099,0.001358951],"study_design_scores_gemma":[0.000252821,0.0007661605,0.0001515802,0.00001281283,0.000005429642,0.00004401906,0.00007274971,0.00001631193,0.9852232,0.0003037626,0.01308572,0.00006544024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605628,0.002082257,0.03665385,0.0001707459,0.0001248255,0.00008164289,0.000006576905,0.000004209675,0.0003131182],"genre_scores_gemma":[0.9933634,0.001365124,0.004698933,0.0002739424,0.0001871672,0.000001180497,0.000009175181,0.000008911122,0.00009215114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03280064,"threshold_uncertainty_score":0.2327648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005555632800893444,"score_gpt":0.2718285985150837,"score_spread":0.2662729657141903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}