{"id":"W2888952975","doi":"10.1039/c8gc01958d","title":"Solvent-free direct α-alkylation of ketones by alcohols catalyzed by nickel supported on silica–alumina","year":2018,"lang":"en","type":"article","venue":"Green Chemistry","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation","keywords":"Acetophenone; Catalysis; Alkylation; Nickel; Chemistry; Alcohol; Solvent; Organic chemistry; Benzyl alcohol; Hydrogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181793,0.000341847,0.0002344642,0.0001322887,0.0001725681,0.0001698151,0.0002486394,0.0001369355,0.0009337822],"category_scores_gemma":[0.0001283311,0.0001213531,0.0001454388,0.0001705045,0.0002544932,0.000285014,0.0002459227,0.0002692185,0.0004777616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001702023,"about_ca_system_score_gemma":0.0001651895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001456561,"about_ca_topic_score_gemma":0.00276487,"domain_scores_codex":[0.9999168,0.000009180384,0.000006561864,0.00001262349,0.00002486166,0.00002988354],"domain_scores_gemma":[0.9999558,0.000008823866,0.0000101691,0.000006480772,0.000009318215,0.000009520913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001968519,0.00001838196,0.0001854506,0.0001799945,0.00001237851,0.0001267878,0.0001007533,0.00008457923,0.9960426,0.0002093797,0.00006416842,0.002778665],"study_design_scores_gemma":[0.00001101002,0.0001629567,0.0009837189,0.000004227947,0.00001160502,0.00008147123,0.00003739502,0.000154795,0.9968938,0.00002734653,0.001625276,0.000006241795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915532,0.002008893,0.001283049,0.00004129342,0.00002630975,0.00001719217,0.0001087582,0.00005241992,0.004908698],"genre_scores_gemma":[0.9969375,0.001001752,0.0004138066,0.00000827111,0.000006916718,0.000003593171,0.00008618151,0.00000766435,0.001534349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001456561,"threshold_uncertainty_score":0.003123879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009390605856755956,"score_gpt":0.23761260355381,"score_spread":0.228221997697054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}