{"id":"W2889012164","doi":"10.1101/405415","title":"Clonotypic Heterogeneity In Cutaneous T-Cell Lymphoma Revealed By Comprehensive Whole Exome/Transcriptome Sequencing","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Bispebjerg Hospital; University of Alberta; Canadian Dermatology Foundation","keywords":"T-cell receptor; Mycosis fungoides; Biology; Transcriptome; Lymphoma; Repertoire; Exome sequencing; Gene rearrangement; T cell; Exome; Peripheral T-cell lymphoma; Immunology; Gene; Genetics; Mutation; Immune system; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002165562,0.0001631691,0.0001793632,0.000560637,0.0001273784,0.000350672,0.0001107101,0.0002241531,0.0008045305],"category_scores_gemma":[0.0003070146,0.00008445336,0.0001869315,0.0003784322,0.0001415013,0.0001325448,0.0002680792,0.0001864016,0.0002417103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009231896,"about_ca_system_score_gemma":0.00006166483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002362626,"about_ca_topic_score_gemma":0.0004879582,"domain_scores_codex":[0.9998611,0.00002325619,0.0000116025,0.00005599631,0.00002624787,0.00002185627],"domain_scores_gemma":[0.9998485,0.0000477454,0.00003671154,0.00002543091,0.0000236882,0.0000178601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001137119,0.0000147583,0.02080251,0.00007825432,0.00006240413,0.0005746288,0.000113325,0.0003450635,0.9665177,0.0001145865,0.0002165348,0.01104654],"study_design_scores_gemma":[0.00002815107,0.0002445533,0.7427771,0.00008130616,0.0004116901,0.009992908,0.0005211777,0.01018979,0.221574,0.00124437,0.01289976,0.00003523941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889818,0.0008659341,0.007354662,0.00006595607,0.000008492522,0.0000172919,0.001933197,0.00006716399,0.0007054424],"genre_scores_gemma":[0.9921664,0.0003743357,0.004625428,0.00009206647,0.000009885936,0.00002288027,0.002273534,0.00002903389,0.0004063748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008045305,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02473748676430964,"score_gpt":0.2659109141328974,"score_spread":0.2411734273685878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}