{"id":"W2889046911","doi":"10.1002/pbc.27431","title":"Generic formulations of imatinib for treatment of Philadelphia chromosome–positive leukemia in pediatric patients","year":2018,"lang":"en","type":"review","venue":"Pediatric Blood & Cancer","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Imatinib; Medicine; Leukemia; Philadelphia chromosome; Internal medicine; Imatinib mesylate; Oncology; Chromosomal translocation; Genetics; Gene; Myeloid leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004057735,0.0003732545,0.0006377398,0.001894453,0.0001976292,0.0006385807,0.0004652058,0.0006421852,0.003817307],"category_scores_gemma":[0.0009676463,0.000132116,0.0005346203,0.001215697,0.0002676323,0.0007963785,0.0003915047,0.001026502,0.0009493677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002413464,"about_ca_system_score_gemma":0.0005093888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004982416,"about_ca_topic_score_gemma":0.001158991,"domain_scores_codex":[0.9997849,0.00004774432,0.00005250188,0.00003133984,0.00007233053,0.0000111109],"domain_scores_gemma":[0.9996418,0.0002184972,0.00007333376,0.000007564881,0.00004464215,0.00001418775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007440916,0.00006098537,0.0003448866,0.02791954,0.0001293192,0.0002886348,0.00007680492,0.0001591165,0.0009645511,0.002101439,0.01883076,0.9490495],"study_design_scores_gemma":[0.00003494121,0.0001331471,0.001968112,0.01277976,0.0003043411,0.0049119,0.0000850057,0.0001006768,0.0005254286,0.00132244,0.9778166,0.00001768298],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002409207,0.9982378,0.00006528851,0.0002690845,0.00009532838,0.000006596359,0.00002477857,0.000003775081,0.001056396],"genre_scores_gemma":[0.001313851,0.9978991,0.0001588772,0.0001910254,0.0001165976,0.000007182542,0.00002877958,0.000001135873,0.0002835414],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003817307,"threshold_uncertainty_score":0.01277024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04851311132027888,"score_gpt":0.3459476988044844,"score_spread":0.2974345874842056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}