{"id":"W2889046911","doi":"10.1002/pbc.27431","title":"Generic formulations of imatinib for treatment of Philadelphia chromosome–positive leukemia in pediatric patients","year":2018,"lang":"en","type":"review","venue":"Pediatric Blood & Cancer","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Imatinib; Medicine; Leukemia; Philadelphia chromosome; Internal medicine; Imatinib mesylate; Oncology; Chromosomal translocation; Genetics; Gene; Myeloid leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001299199,0.0008449549,0.003528716,0.001038383,0.00006540511,0.000008157142,0.0002484688,0.0005548486,0.0001604205],"category_scores_gemma":[0.0001104543,0.0006781452,0.001105628,0.00166507,0.00007975336,0.0001043187,0.00007556421,0.0001674406,0.00001666862],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.004676754,"about_ca_system_score_gemma":0.006670497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004437716,"about_ca_topic_score_gemma":0.00008082099,"domain_scores_codex":[0.9958153,0.00008810562,0.002040118,0.0008526623,0.0005485379,0.0006552414],"domain_scores_gemma":[0.9961232,0.0004886589,0.0019425,0.000741299,0.0004882286,0.0002161095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0007719362,0.01192001,0.1371292,0.269864,0.00663613,0.00007190375,0.002095534,0.00007966169,0.000004126503,0.0000805357,0.004998327,0.5663486],"study_design_scores_gemma":[0.1491143,0.03190212,0.06017219,0.02820838,0.3836612,0.0001442052,0.00005709515,0.0004661732,0.0004172316,0.0002296992,0.3395135,0.006113909],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03327681,0.9577792,0.00001082369,0.00001130211,0.0004460859,0.005565338,0.002698442,0.0000341355,0.0001778748],"genre_scores_gemma":[0.005347771,0.9862141,0.001240005,0.00001093196,0.002668087,0.002570685,0.00164399,0.0001631133,0.0001412965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5602347,"threshold_uncertainty_score":0.999567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04851311132027888,"score_gpt":0.3459476988044844,"score_spread":0.2974345874842056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}