{"id":"W2889141154","doi":"10.1242/dmm.035147","title":"The relationship between sex hormones, the vaginal microbiome and immunity in HIV-1 susceptibility in women","year":2018,"lang":"en","type":"review","venue":"Disease Models & Mechanisms","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network; Council of Ontario Universities","keywords":"Bacterial vaginosis; Medroxyprogesterone acetate; Hormone; Biology; Estrogen; Immunology; Immune system; Lactobacillus; Physiology; Hormonal contraception; Microbiome; Population; Medicine; Endocrinology; Bioinformatics; Microbiology; Family planning","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005848433,0.0002034968,0.0003286952,0.0004635069,0.0003439068,0.0007773001,0.000220091,0.0005530003,0.002858735],"category_scores_gemma":[0.002292227,0.0002043601,0.0007587976,0.0009208987,0.0002145759,0.0003533872,0.0003458229,0.0006915906,0.0001634873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002454666,"about_ca_system_score_gemma":0.0002924148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003443265,"about_ca_topic_score_gemma":0.003441386,"domain_scores_codex":[0.9996823,0.0001230491,0.00003267705,0.00006343122,0.00004323443,0.00005528245],"domain_scores_gemma":[0.9992532,0.0003091699,0.0002623936,0.00003215049,0.00006672146,0.00007635614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006967785,0.00005222427,0.9818525,0.0004906259,0.0007695869,0.0001063094,0.0001556054,0.00005529924,0.0003221569,0.0001379362,0.000585093,0.01477586],"study_design_scores_gemma":[0.00003739899,0.0002854315,0.9938013,0.000404617,0.0009735076,0.0003861495,0.0004716793,0.0003458645,0.0001607899,0.0004319132,0.002688024,0.00001344463],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8719503,0.1201939,0.0003340426,0.001600207,0.0002485713,0.00003451563,0.001818525,0.00001094623,0.003809072],"genre_scores_gemma":[0.9926594,0.006202473,0.0001532649,0.0002240812,0.00008550666,0.00001529533,0.000220601,0.000002660269,0.0004368146],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003443265,"threshold_uncertainty_score":0.009563386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08490225781445035,"score_gpt":0.3450181613301753,"score_spread":0.260115903515725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}