{"id":"W2889142294","doi":"10.1002/adtp.201800038","title":"Controlled Non‐Viral Gene Delivery in Cartilage and Bone Repair: Current Strategies and Future Directions","year":2018,"lang":"en","type":"article","venue":"Advanced Therapeutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"European Research Council; Advanced Materials and Bioengineering Research; Science Foundation Ireland","keywords":"Gene delivery; Genetic enhancement; Regeneration (biology); Transduction (biophysics); Viral vector; Regenerative medicine; Biology; Gene; Bioinformatics; Medicine; Cell biology; Stem cell; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003473139,0.0007419448,0.0008785353,0.001077268,0.0003857671,0.002635226,0.001455515,0.002252112,0.003542039],"category_scores_gemma":[0.0007816696,0.0003711357,0.0005011556,0.0008768243,0.001912194,0.003452175,0.0008134871,0.001617885,0.00137675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001089578,"about_ca_system_score_gemma":0.001575007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007101216,"about_ca_topic_score_gemma":0.001268446,"domain_scores_codex":[0.9994615,0.0001410188,0.00005169598,0.00009520043,0.0001640852,0.00008658629],"domain_scores_gemma":[0.9992193,0.0003528351,0.0001214633,0.00003487366,0.0001624295,0.0001089839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005204295,0.0009757399,0.0008833096,0.01148993,0.00009978505,0.0005080171,0.0004945889,0.002999396,0.07356421,0.03828932,0.01027037,0.859905],"study_design_scores_gemma":[0.0002254333,0.003032021,0.002599649,0.004153059,0.000291091,0.002792282,0.001308676,0.007041833,0.08253255,0.04576872,0.8500033,0.0002513174],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004747832,0.97856,0.01027454,0.003091386,0.0002240807,0.00004028145,0.00003222599,0.00007845115,0.002951193],"genre_scores_gemma":[0.04256347,0.9410447,0.0117617,0.001238704,0.0006093135,0.0001596091,0.0001114213,0.00002541555,0.002485617],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003542039,"threshold_uncertainty_score":0.01836789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009670644528970328,"score_gpt":0.2698992024739791,"score_spread":0.2602285579450088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}