{"id":"W2889146759","doi":"10.3748/wjg.v24.i32.3567","title":"Positioning of old and new biologicals and small molecules in the treatment of inflammatory bowel diseases","year":2018,"lang":"en","type":"review","venue":"World Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"Pfizer","keywords":"Medicine; Inflammatory bowel disease; Vedolizumab; Ulcerative colitis; Intensive care medicine; Disease; Crohn's disease; Clinical trial; Targeted therapy; Bioinformatics; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008522409,0.001041255,0.001353764,0.00237824,0.0004170384,0.001146896,0.001065417,0.001403673,0.002552267],"category_scores_gemma":[0.001096931,0.000252769,0.00046471,0.002674074,0.000943643,0.002193423,0.0008287916,0.00271127,0.00244316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00080122,"about_ca_system_score_gemma":0.001120724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006723746,"about_ca_topic_score_gemma":0.001026575,"domain_scores_codex":[0.9996141,0.0000931891,0.00005027596,0.00006090271,0.0001502778,0.0000312814],"domain_scores_gemma":[0.9995285,0.000235163,0.00006099701,0.00001808372,0.0001167962,0.00004041287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000100913,0.00007124505,0.0001341278,0.01487363,0.00005867694,0.0002002961,0.0001001607,0.0004538213,0.001686662,0.007113503,0.04381904,0.931388],"study_design_scores_gemma":[0.00001285332,0.00008089314,0.0003502271,0.00269001,0.00005027681,0.0009058755,0.00005120184,0.00005853861,0.0002743138,0.002973609,0.9925388,0.00001347043],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006313859,0.9984487,0.0001181188,0.0003699915,0.0004158786,0.000002702264,0.000006803424,0.000008053173,0.0005665758],"genre_scores_gemma":[0.0005059949,0.9982816,0.0002232864,0.0002819491,0.000269464,0.000005091227,0.0000113547,0.000001784287,0.0004194559],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002552267,"threshold_uncertainty_score":0.008538187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02119692321577423,"score_gpt":0.2746608672047792,"score_spread":0.253463943989005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}