{"id":"W2889150696","doi":"10.1016/j.celrep.2018.07.090","title":"Rapid and Integrative Discovery of Retina Regulatory Molecules","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Eye Institute; National Human Genome Research Institute; Intellectual and Developmental Disabilities Research Center; Boston Medical Center; National Institutes of Health; Cancer Prevention and Research Institute of Texas; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Robert and Janice McNair Foundation; National Institute on Aging; Brain Research Foundation","keywords":"Retina; Retinal; Biology; Neuroscience; Genetic screen; Gene; Computational biology; Mutant; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009256763,0.0004566392,0.0004251881,0.0007498079,0.0002910189,0.0009904819,0.0005146369,0.0003012668,0.001814357],"category_scores_gemma":[0.0003650907,0.0003121048,0.0004673046,0.0003148561,0.0004016231,0.0004255849,0.0006773818,0.0009183051,0.0006390763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005598051,"about_ca_system_score_gemma":0.0008638725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006228028,"about_ca_topic_score_gemma":0.001311247,"domain_scores_codex":[0.9996334,0.00003526824,0.00002253919,0.00007187903,0.0001915859,0.00004522873],"domain_scores_gemma":[0.9998022,0.00005290216,0.00003780891,0.000031982,0.00003695399,0.00003822119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007460559,0.00005302244,0.0005683632,0.00008247846,0.00002199844,0.0001251077,0.00003238051,0.0005424438,0.9704151,0.004264631,0.0004337984,0.02338605],"study_design_scores_gemma":[0.00009733332,0.000373373,0.003662076,0.00002760243,0.00007514581,0.0005387504,0.00006152098,0.005011126,0.9510328,0.001532166,0.03756605,0.00002201927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7288166,0.008943939,0.2370905,0.001703679,0.000268422,0.0008156121,0.004124133,0.001767076,0.01646993],"genre_scores_gemma":[0.6725991,0.01368485,0.292953,0.0006581298,0.0001042308,0.0004858992,0.008521382,0.0003665682,0.0106268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001814357,"threshold_uncertainty_score":0.00606966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004823788903031478,"score_gpt":0.2111448911601602,"score_spread":0.2063211022571287,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}