{"id":"W2889169204","doi":"10.1139/bcb-2017-0321","title":"Small hepatitis delta antigen selectively binds to target mRNA in hepatic cells: a potential mechanism by which hepatitis D virus downregulates glutathione <i>S</i>-transferase P1 and induces liver injury and hepatocarcinogenesis","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Department of Science and Technology of Sichuan Province; University of Ottawa","keywords":"Virology; Liver injury; Antigen; Glutathione; Hepatitis B virus; Transferase; Messenger RNA; Hepatitis; Virus; Glutathione S-transferase; Chemistry; Biology; Molecular biology; Enzyme; Immunology; Biochemistry; Gene; Pharmacology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310346,0.00024716,0.0001820107,0.000147852,0.0001555654,0.0002120529,0.0001124092,0.0002341952,0.0009916291],"category_scores_gemma":[0.00008745553,0.0000980145,0.000203053,0.0001129868,0.0002361437,0.0001541316,0.0001717806,0.0002559908,0.0003152661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001953013,"about_ca_system_score_gemma":0.0001397652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003770638,"about_ca_topic_score_gemma":0.0005490268,"domain_scores_codex":[0.9998991,0.00002317436,0.000008430128,0.00002455741,0.00002163223,0.00002305277],"domain_scores_gemma":[0.9999534,0.00001070552,0.00001041182,0.000008461105,0.000008372066,0.000008711327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004278861,0.00001211479,0.0005383597,0.000039292,0.000002926634,0.00004280881,0.00001392076,0.00001389208,0.9981229,0.00007593672,0.00001755766,0.00107747],"study_design_scores_gemma":[0.000009412687,0.0002679226,0.01104806,0.000004675134,0.00001324351,0.0002451349,0.00005080712,0.0004758972,0.9863685,0.00005465346,0.001458457,0.000003225894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924659,0.002140111,0.004154643,0.0001205636,0.00003422035,0.00002652041,0.00008776907,0.00004964333,0.0009206435],"genre_scores_gemma":[0.996677,0.0006464924,0.0009758183,0.00007704991,0.00000717296,0.00001978579,0.0001521833,0.000007228749,0.001437326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009916291,"threshold_uncertainty_score":0.003317356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00933726902644963,"score_gpt":0.2213052261735096,"score_spread":0.2119679571470599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}