{"id":"W2889169204","doi":"10.1139/bcb-2017-0321","title":"Small hepatitis delta antigen selectively binds to target mRNA in hepatic cells: a potential mechanism by which hepatitis D virus downregulates glutathione <i>S</i>-transferase P1 and induces liver injury and hepatocarcinogenesis","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Department of Science and Technology of Sichuan Province; University of Ottawa","keywords":"Virology; Liver injury; Antigen; Glutathione; Hepatitis B virus; Transferase; Messenger RNA; Hepatitis; Virus; Glutathione S-transferase; Chemistry; Biology; Molecular biology; Enzyme; Immunology; Biochemistry; Gene; Pharmacology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002698513,0.000476602,0.0007081471,0.0001661075,0.000281749,0.00004127237,0.0001224498,0.0004989599,0.00007173747],"category_scores_gemma":[0.00008836553,0.0004583566,0.00005307557,0.0003866407,0.0004277779,0.00006763007,0.0002157679,0.0002591697,0.000009333845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006873066,"about_ca_system_score_gemma":0.0001271662,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01829523,"about_ca_topic_score_gemma":0.005081685,"domain_scores_codex":[0.9976416,0.0001443291,0.0004828666,0.0009670235,0.0001440277,0.0006201004],"domain_scores_gemma":[0.9989655,0.00009073337,0.0001021626,0.0002498988,0.0002143077,0.0003774131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002616553,0.0001497284,0.1808509,0.0002018144,0.00008796041,0.00006911461,0.0006476935,9.382234e-8,0.8149782,0.000006782513,0.00030683,0.002439215],"study_design_scores_gemma":[0.0009903031,0.001295594,0.06567265,0.0001125665,0.0001073851,0.0000928855,0.00005481139,0.0002639127,0.9303917,0.0001668011,0.0003741173,0.0004772421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923858,0.005666958,0.000206396,0.0002355079,0.0001431531,0.0005512742,0.0005973673,0.0000573434,0.0001561671],"genre_scores_gemma":[0.9754918,0.02179936,0.001549139,0.0005801456,0.0001718693,0.00008777295,0.0001421454,0.00004139034,0.0001364042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1154136,"threshold_uncertainty_score":0.9997868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00933726902644963,"score_gpt":0.2213052261735096,"score_spread":0.2119679571470599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}