{"id":"W2889196632","doi":"10.1080/15548627.2018.1491494","title":"CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Phagosome; Biology; Burkholderia cenocepacia; Autophagy; Autophagosome; Phagolysosome; Cell biology; Intracellular parasite; Inflammasome; Microbiology; Legionella pneumophila; Intracellular; Bacteria; Inflammation; Apoptosis; Immunology; Biochemistry; Burkholderia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030941,0.0002917423,0.0004229651,0.0004866185,0.0002273321,0.0003964319,0.0002037836,0.0004202035,0.00200152],"category_scores_gemma":[0.0002920511,0.000162948,0.0004037907,0.0001883679,0.0003706946,0.000395914,0.0004002624,0.0007584878,0.000618023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004749299,"about_ca_system_score_gemma":0.0002747495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002924393,"about_ca_topic_score_gemma":0.000235815,"domain_scores_codex":[0.9997016,0.00006742433,0.00003716019,0.00003924778,0.00006436632,0.00009022019],"domain_scores_gemma":[0.9997764,0.0000395554,0.00005462915,0.00002943873,0.00004054196,0.00005954147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007236506,0.00006210101,0.0005036795,0.00006443114,0.000007807854,0.0001374691,0.00001785344,0.00006176718,0.9972024,0.00007044581,0.00008347565,0.00106503],"study_design_scores_gemma":[0.00005291589,0.0003809111,0.0123009,0.0000135828,0.00001526397,0.0007453152,0.00006950994,0.0009698686,0.98395,0.000157783,0.001336347,0.00000760385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995167,0.001889012,0.001148629,0.0001515415,0.00004872364,0.0000267879,0.0002489235,0.0000845364,0.001234831],"genre_scores_gemma":[0.9963115,0.0005962552,0.001095143,0.00004059859,0.0000160667,0.00004846543,0.0003351331,0.0000120535,0.001544892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00200152,"threshold_uncertainty_score":0.006695747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739160550371195,"score_gpt":0.3012460331125204,"score_spread":0.2838544276088085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}