{"id":"W2889196632","doi":"10.1080/15548627.2018.1491494","title":"CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection","year":2018,"lang":"en","type":"article","venue":"Autophagy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Center for Advancing Translational Sciences; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Phagosome; Biology; Burkholderia cenocepacia; Autophagy; Autophagosome; Phagolysosome; Cell biology; Intracellular parasite; Inflammasome; Microbiology; Legionella pneumophila; Intracellular; Bacteria; Inflammation; Apoptosis; Immunology; Biochemistry; Burkholderia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004314498,0.000223532,0.0003202614,0.0004390427,0.0001116053,0.00004308915,0.00009304899,0.0001678264,0.001078902],"category_scores_gemma":[0.0002958204,0.0002088783,0.00009680865,0.000567653,0.00007630231,0.0003751037,0.00005184147,0.0001364857,0.0008850425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002365543,"about_ca_system_score_gemma":0.0001528321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002224537,"about_ca_topic_score_gemma":0.0001723846,"domain_scores_codex":[0.998381,0.0001709462,0.0004192235,0.0003453293,0.0002729636,0.000410533],"domain_scores_gemma":[0.9990202,0.00007450992,0.00009463367,0.0004310992,0.0001389169,0.0002406633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.009493691,0.0008179363,0.003490621,0.0001195072,0.0000740212,0.0006536419,0.004466112,0.000007384636,0.9578222,0.0006730033,0.002296696,0.02008516],"study_design_scores_gemma":[0.003564906,0.001814759,0.4941612,0.0001434254,0.00004353582,0.0002336586,0.00003233133,0.0006748,0.4801755,0.0004618841,0.0184199,0.000274108],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962077,0.0000554614,0.0003291493,0.0009610092,0.0007056309,0.000841844,0.00001301445,0.0002503113,0.0006359147],"genre_scores_gemma":[0.9965063,0.00001006569,0.0004269234,0.001163496,0.0007571474,0.0001088673,0.00004418547,0.00003861364,0.000944381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4906706,"threshold_uncertainty_score":0.9998929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739160550371195,"score_gpt":0.3012460331125204,"score_spread":0.2838544276088085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}