{"id":"W2889214539","doi":"10.1111/cmi.12949","title":"An extracellular <scp> <i>Leptospira interrogans</i> </scp> leucine‐rich repeat protein binds human E‐ and VE‐cadherins","year":2018,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Leptospirosis research and findings","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Genome British Columbia; University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche; National Institutes of Health; Agence Nationale de la Recherche; Pasteur Foundation","keywords":"Biology; Extracellular; Leptospira interrogans; Cadherin; Leptospira; Leucine-rich repeat; Leucine; Cell biology; Microbiology; Computational biology; Biochemistry; Cell; Amino acid; Serotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00078885,0.0006039649,0.000724213,0.0003636061,0.0008168648,0.00009984843,0.0009146505,0.001099399,0.0009029084],"category_scores_gemma":[0.0001647549,0.0005504673,0.000170904,0.0003529732,0.002220188,0.0002579987,0.0004570468,0.001016062,0.001898955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009831486,"about_ca_system_score_gemma":0.00009537682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001086544,"about_ca_topic_score_gemma":0.00007310193,"domain_scores_codex":[0.9957878,0.0005920575,0.0007037299,0.001326823,0.00005234977,0.001537263],"domain_scores_gemma":[0.9981806,0.0000987233,0.0002731335,0.001027377,0.0002306233,0.0001896017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004578257,0.0002994454,0.003379924,0.00004425652,0.0001775248,0.00004598814,0.001504209,1.446054e-7,0.9867496,0.0007142457,0.00623271,0.0008061649],"study_design_scores_gemma":[0.001513759,0.002269629,0.0004627323,0.00003954663,0.00003705783,0.0001985562,0.0004768395,0.000002346623,0.7425167,0.0001060081,0.2521518,0.0002250317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907176,0.005073257,0.0004912075,0.0001434555,0.0005672334,0.0008024777,0.00009938098,0.0002556125,0.00184975],"genre_scores_gemma":[0.9811034,0.00005317644,0.0002462291,0.0003050638,0.0002880789,0.00008000049,0.0009662319,0.00009445472,0.01686337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2459191,"threshold_uncertainty_score":0.9996947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01297179273155205,"score_gpt":0.2458461484499832,"score_spread":0.2328743557184312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}