{"id":"W2889297418","doi":"10.1038/s41598-018-31500-8","title":"Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Universitair Medisch Centrum Groningen; Vlaamse regering; Vlaams Instituut voor Biotechnologie","keywords":"Adherens junction; Respiratory epithelium; Lung; Epithelium; Pathology; Cadherin; Mucus; Biology; Immunology; Goblet cell; Chemokine; Alveolar Epithelium; Metaplasia; Medicine; Inflammation; Cell; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006471993,0.0008951409,0.000758627,0.001430091,0.000648729,0.0007269346,0.0007170259,0.001275756,0.003815873],"category_scores_gemma":[0.0004127047,0.0004300142,0.0006124183,0.0003370591,0.0008570363,0.0009768999,0.0004594758,0.001910206,0.0009071019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005481842,"about_ca_system_score_gemma":0.0004446077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005913422,"about_ca_topic_score_gemma":0.001051459,"domain_scores_codex":[0.9993922,0.00007174745,0.0000889478,0.000192647,0.0001349043,0.0001196378],"domain_scores_gemma":[0.9993154,0.0001234863,0.0001448742,0.0000831991,0.00006508015,0.0002680526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002105502,0.0003405297,0.0003773875,0.00005794152,0.000009883154,0.0003069986,0.00003285148,0.00007554585,0.9966938,0.0005213379,0.0000906494,0.001282426],"study_design_scores_gemma":[0.0002413478,0.003153038,0.01233421,0.0000718284,0.0001689653,0.003430804,0.0001967729,0.003431956,0.9682878,0.0005674451,0.008074811,0.00004098416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682138,0.002327679,0.02265687,0.0007246908,0.0002150622,0.000571279,0.002173464,0.0004832857,0.002634006],"genre_scores_gemma":[0.9632328,0.002459332,0.01793093,0.0003048549,0.00007802043,0.0009108373,0.002666492,0.0001826884,0.01223417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003815873,"threshold_uncertainty_score":0.01276535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05914106938499549,"score_gpt":0.3798650450368057,"score_spread":0.3207239756518102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}