{"id":"W2889355272","doi":"10.1093/eurheartj/ehy566.5069","title":"5069Reversal of apixaban and rivaroxaban anticoagulation by andexanet alfa in ANNEXA-A&R as assessed by non-tissue factor (TF)-initiated thrombin generation independent of TF pathway inhibitor (TFPI)","year":2018,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University; St. Joseph's Hospital","funders":"","keywords":"Medicine; Apixaban; Rivaroxaban; Tissue factor pathway inhibitor; Tissue factor; Thrombin generation; Thrombin; Pharmacology; Cardiology; Internal medicine; Coagulation; Atrial fibrillation; Warfarin; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00100071,0.0004205131,0.0006185306,0.0001622776,0.0001926163,0.0005212461,0.0001869827,0.0003233659,0.00269295],"category_scores_gemma":[0.0008310316,0.0001340288,0.0005655478,0.0001389617,0.0002378162,0.0002058429,0.0002320078,0.0006019002,0.0005125068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002145374,"about_ca_system_score_gemma":0.0002515751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003808538,"about_ca_topic_score_gemma":0.0003755648,"domain_scores_codex":[0.9994031,0.0002094688,0.00007614638,0.0001131205,0.0001175518,0.00008057954],"domain_scores_gemma":[0.9996567,0.00006825717,0.000106069,0.00006048427,0.00003092288,0.00007764957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.3101265,0.01257727,0.159105,0.0005700809,0.001867796,0.003183124,0.0008283245,0.0004915879,0.3140674,0.0007818851,0.002968329,0.1934327],"study_design_scores_gemma":[0.009096542,0.1759733,0.7012458,0.00008515838,0.001105536,0.006437454,0.0003610697,0.002513463,0.08317529,0.0002372311,0.01970303,0.00006611031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972501,0.001153413,0.0002675351,0.00003560799,0.00002759356,0.0000783318,0.0001085743,0.00001607179,0.001062678],"genre_scores_gemma":[0.9970366,0.0003700679,0.0003961299,0.00008057939,0.00003271057,0.00008179535,0.0003173314,0.00000767519,0.001677204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00269295,"threshold_uncertainty_score":0.009008765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1153403743482183,"score_gpt":0.3633182273942384,"score_spread":0.2479778530460202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}