{"id":"W2889412507","doi":"10.1182/blood-2018-03-840702","title":"SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":175,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; BC Children's Hospital; Université de Montréal; University of Manitoba; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Severe combined immunodeficiency; Medicine; Immune system; Transplantation; Internal medicine; Immunosuppression; Hematopoietic stem cell transplantation; Genotype; Survival analysis; Immunology; Regimen; Oncology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006685912,0.000359497,0.0003221879,0.0006461392,0.0002898343,0.0006842078,0.0003550503,0.0005414909,0.005809719],"category_scores_gemma":[0.002651113,0.00008943756,0.0004272315,0.000519571,0.0003794764,0.0004499221,0.0003533458,0.0007270628,0.0007669886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002653087,"about_ca_system_score_gemma":0.0002348974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008800983,"about_ca_topic_score_gemma":0.001099325,"domain_scores_codex":[0.99977,0.00006426824,0.00002897694,0.00003663913,0.00005197908,0.00004824392],"domain_scores_gemma":[0.9982114,0.0004504395,0.0007781105,0.00009159506,0.0001397337,0.0003288032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006305067,0.00006688626,0.988649,0.00002549508,0.0001032061,0.0001151737,0.00001283602,0.0002146497,0.0007644944,0.00005686316,0.0006581611,0.008702831],"study_design_scores_gemma":[0.00001179212,0.0002352274,0.9967133,0.00005505107,0.00009344751,0.0008570063,0.00005001055,0.0005569163,0.0005748414,0.0002090511,0.0006355291,0.000007844174],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931866,0.001729293,0.0003303119,0.0004298057,0.00003826322,0.00001274967,0.001064797,0.00003268548,0.003175515],"genre_scores_gemma":[0.9975808,0.0003377006,0.0002985107,0.00008799941,0.00004045763,0.000006698981,0.001053659,0.000004494851,0.0005897165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005809719,"threshold_uncertainty_score":0.01943547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006313346357264111,"score_gpt":0.1973496933613886,"score_spread":0.1910363470041244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}