{"id":"W2889466173","doi":"10.2147/ndt.s173280","title":"Neurofilament light chain as a biological marker for multiple sclerosis: a meta-analysis study","year":2018,"lang":"en","type":"review","venue":"Neuropsychiatric Disease and Treatment","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Meta-analysis; Multiple sclerosis; Internal medicine; Biomarker; Cerebrospinal fluid; Subgroup analysis; Oncology; Publication bias; Immunology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003472977,0.001220092,0.005503688,0.0009110555,0.0004055771,0.000125883,0.0002443468,0.0001559046,0.0002105306],"category_scores_gemma":[0.0004107063,0.0006529381,0.006152407,0.0013359,0.0001331596,0.0000433983,0.0002618049,0.0002122596,0.0000943762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001668759,"about_ca_system_score_gemma":0.0003240666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007971081,"about_ca_topic_score_gemma":0.00004199846,"domain_scores_codex":[0.9946073,0.0008360605,0.001054117,0.002065567,0.0006783275,0.0007585849],"domain_scores_gemma":[0.9962757,0.0007469726,0.0004134075,0.001336046,0.0001794817,0.001048398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002036605,0.01767505,0.007254148,0.004624855,0.703598,0.0004128062,0.0001955915,6.290585e-7,8.163225e-7,0.00001568919,0.002167494,0.2620184],"study_design_scores_gemma":[0.002786064,0.005272995,0.0124595,0.0001391614,0.6152903,0.000006198125,0.00004316323,0.00002744371,1.204715e-7,0.00000404735,0.3635707,0.0004002881],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002567526,0.9825748,0.000005801676,0.0004897477,0.0001712809,0.0131668,0.0007850754,0.0001185982,0.0001203845],"genre_scores_gemma":[0.005386545,0.9803724,0.0001843374,0.0002040085,0.0004580605,0.01189262,0.0003124947,0.000109006,0.001080535],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3614032,"threshold_uncertainty_score":0.9995922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3043738414634864,"score_gpt":0.3991873825819871,"score_spread":0.09481354111850065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}