{"id":"W2889565965","doi":"10.1111/desc.12739","title":"Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood","year":2018,"lang":"en","type":"article","venue":"Developmental Science","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Learning Partnership; Simon Fraser University; BC Children's Hospital; Canadian Institute for Advanced Research; University of British Columbia","funders":"National Institute of Mental Health","keywords":"Psychology; Reactivity (psychology); Developmental psychology; Young adult; DNA methylation; Clinical psychology; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004715534,0.00009578781,0.00006715591,0.000107545,0.0001517311,0.00003041354,0.0001457911,0.0000517269,0.00000369533],"category_scores_gemma":[0.00008902918,0.00009660677,0.000009959403,0.0003463931,0.0001859414,0.00001929788,0.0001971339,0.00004539773,0.000007257977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004437119,"about_ca_system_score_gemma":0.0001052074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003480277,"about_ca_topic_score_gemma":0.0001658989,"domain_scores_codex":[0.9989801,0.00002229983,0.0001347957,0.0004249469,0.0001996671,0.0002381612],"domain_scores_gemma":[0.9996681,0.000002138459,0.00004008157,0.0001104446,0.00006394901,0.0001152809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001146129,0.00002988401,0.1346951,0.000001492944,5.951976e-7,3.545995e-7,0.0003826505,0.000001743995,0.8006049,0.000009107291,0.00000323825,0.06425952],"study_design_scores_gemma":[0.0001091734,0.00009594491,0.5657735,0.00001163652,8.879941e-7,0.000001343358,0.00004753236,0.00001943942,0.4335948,0.00002103436,0.0002362901,0.00008833696],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983729,0.0001074902,0.0007854524,0.00006425883,0.0000972912,0.0001877243,0.000003754767,0.000007760436,0.0003733859],"genre_scores_gemma":[0.9949592,0.00007049459,0.004806786,0.00004707343,0.00007784164,0.000009800991,0.00001093165,0.000006039144,0.00001176794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4310785,"threshold_uncertainty_score":0.393951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295999688628161,"score_gpt":0.2784955136773,"score_spread":0.2655355167910183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}