{"id":"W2889576382","doi":"10.1200/jco.2017.35.15_suppl.11587","title":"Impact and correlation of mutational load (ML) and specific mutations (mts) assessed by limited targeted profiling (LTP) with PD-L1 tumour expression (exp) in resected non-small cell lung carcinoma (NSCLC).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; non-small cell lung cancer (NSCLC); Oncology; Targeted therapy; Internal medicine; Lung cancer; Immunotherapy; Pathology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007448377,0.0001580388,0.0001895046,0.0005056592,0.0001519982,0.0003931187,0.0002001533,0.0002572923,0.0009571991],"category_scores_gemma":[0.001705542,0.000138675,0.0001609293,0.0002540641,0.0002216652,0.000294532,0.0003875831,0.0002137675,0.000255332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002282872,"about_ca_system_score_gemma":0.0001021012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004928772,"about_ca_topic_score_gemma":0.001095655,"domain_scores_codex":[0.9996736,0.0001110482,0.00004601798,0.00007194557,0.00005919729,0.00003820592],"domain_scores_gemma":[0.9989501,0.0004209412,0.0003639345,0.00005038071,0.00007426122,0.0001404335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005209685,0.00002288502,0.9957103,0.000008624464,0.00001809108,0.00008277446,0.00002903117,0.00006224408,0.001627947,0.000004216509,0.00003098494,0.001881993],"study_design_scores_gemma":[0.000007257118,0.0003681894,0.9978422,0.000002384382,0.00002399882,0.0004878125,0.00006638825,0.000508121,0.0005864433,0.0000095281,0.00009560755,0.000001991563],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996586,0.0001130781,0.00005343198,0.000008674384,0.000001019096,0.000003058814,0.00006521038,0.000001582567,0.00009520631],"genre_scores_gemma":[0.9997769,0.00001864729,0.00004992635,0.000005996858,0.000002098913,0.000002918385,0.00009728938,7.701495e-7,0.00004535246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009571991,"threshold_uncertainty_score":0.003939092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0318163345960466,"score_gpt":0.3624763704538503,"score_spread":0.3306600358578037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}