{"id":"W2889692270","doi":"10.1038/s41379-018-0126-3","title":"The role of a monoclonal antibody 11C8B1 as a diagnostic marker of IDH2-mutated sinonasal undifferentiated carcinoma","year":2018,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Head and Neck Surgical Oncology","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"IDH2; IDH1; Pathology; Immunohistochemistry; Intrahepatic Cholangiocarcinoma; Monoclonal antibody; Biology; Carcinoma; Hematopathology; Chondrosarcoma; Cancer research; Mutation; Medicine; Antibody; Immunology; Cytogenetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003187028,0.0001762189,0.0006141069,0.0001023074,0.00008467143,0.000003808726,0.0001569341,0.0002539473,0.0002996164],"category_scores_gemma":[0.0005552245,0.0001172314,0.0001404674,0.0001575992,0.0008084954,0.00002408332,0.0001078431,0.000220294,0.00008111199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003049094,"about_ca_system_score_gemma":0.0002095137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001008562,"about_ca_topic_score_gemma":0.00004421544,"domain_scores_codex":[0.9982454,0.0003015877,0.0005149254,0.0003107521,0.0002086451,0.0004187297],"domain_scores_gemma":[0.9980573,0.0009709527,0.0001810485,0.0003824203,0.0002730803,0.0001351707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002370733,0.0007851092,0.4803455,0.00004502482,0.0001507251,0.0008231834,0.0009865247,0.000001719292,0.4968261,0.001373501,0.0000968645,0.016195],"study_design_scores_gemma":[0.002769913,0.003173622,0.9349569,0.00005218458,0.0001788717,0.0008316072,0.00008284628,0.005450597,0.04193364,0.008794392,0.001627004,0.0001484051],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932217,0.001144196,0.0002790548,0.0004478824,0.000189271,0.0003054439,0.00002477686,0.0000325855,0.004355114],"genre_scores_gemma":[0.9991646,0.00008783206,0.0001101828,0.0001986167,0.0001054805,0.00001872783,0.00005005837,0.00002588446,0.0002386416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4548925,"threshold_uncertainty_score":0.4780558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01042666058095747,"score_gpt":0.2971451808099322,"score_spread":0.2867185202289747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}