{"id":"W2889695061","doi":"10.1111/jcmm.13810","title":"P‐Glycoprotein (P‐gp)/<scp>ABCB</scp>1 plays a functional role in extravillous trophoblast (<scp>EVT</scp>) invasion and is decreased in the pre‐eclamptic placenta","year":2018,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Institute of Human Development, Child and Youth Health; Canadian Institutes of Health Research; York University; McGill University","keywords":"Syncytiotrophoblast; Cytotrophoblast; Trophoblast; Biology; Placenta; Cell biology; Gene silencing; Andrology; Genetics; Gene; Fetus; Pregnancy; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001273257,0.0003463309,0.0007466046,0.0004405074,0.0001386838,0.00002808537,0.0001825399,0.0001856805,0.000025911],"category_scores_gemma":[0.001046443,0.0002231783,0.000125252,0.0003998638,0.0004701773,0.0001244097,0.00008337258,0.0007462562,0.000004033081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006252794,"about_ca_system_score_gemma":0.0001597933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008517445,"about_ca_topic_score_gemma":0.00006175147,"domain_scores_codex":[0.9973012,0.0002692137,0.0007966802,0.0003550547,0.0008335927,0.0004443101],"domain_scores_gemma":[0.9984129,0.000467919,0.0003445321,0.000308944,0.0001725973,0.0002931284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008002148,0.0005939021,0.02859383,0.0004297731,0.0003583675,0.003456978,0.01996374,0.0000100851,0.9368055,0.0002954785,0.00441058,0.004281478],"study_design_scores_gemma":[0.05583693,0.01445996,0.500515,0.01299063,0.002134805,0.01214193,0.02088584,0.001787582,0.3247167,0.009064882,0.04500807,0.0004576806],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9514854,0.0418026,0.002315531,0.001262808,0.0001684402,0.0006110654,0.000004040031,0.000009932357,0.002340177],"genre_scores_gemma":[0.9947627,0.001975625,0.0003425903,0.002208535,0.0004446662,0.00002020986,0.00001235969,0.0000314803,0.0002017998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6120889,"threshold_uncertainty_score":0.9100946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01265146805475281,"score_gpt":0.2339787637492144,"score_spread":0.2213272956944616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}