{"id":"W2889849322","doi":"10.1534/genetics.118.301510","title":"Effects of Transmission Bottlenecks on the Diversity of Influenza A Virus","year":2018,"lang":"en","type":"article","venue":"Genetics","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Transmission (telecommunications); Genetics; Virus; Mutation; Population bottleneck; Viral evolution; Influenza A virus; Genetic diversity; Population; Bottleneck; Host (biology); Virology; Gene; Evolutionary biology; Allele; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001422606,0.0002998787,0.0004430869,0.0004939726,0.000431291,0.0006743962,0.0004475626,0.0004741275,0.0006999279],"category_scores_gemma":[0.00722175,0.000247544,0.0003691636,0.0001756171,0.0004579777,0.0008472436,0.0006665711,0.0005585552,0.0000834229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008936737,"about_ca_system_score_gemma":0.0003211134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001658705,"about_ca_topic_score_gemma":0.0007987992,"domain_scores_codex":[0.9996574,0.0001068786,0.0000213209,0.00007539608,0.00005933005,0.00007961104],"domain_scores_gemma":[0.9955109,0.00278909,0.0008686365,0.0002303581,0.0002474026,0.0003535099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.001258804,0.0004272579,0.1297043,0.0001743051,0.0003464386,0.001281139,0.0002701658,0.4963295,0.3393787,0.01491432,0.0003703985,0.01554476],"study_design_scores_gemma":[0.00005854277,0.00121984,0.08105191,0.00002777334,0.0001463871,0.0006121503,0.0002792842,0.8582242,0.04946855,0.00832314,0.0005118133,0.00007642162],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974776,0.00008044177,0.002063364,0.00002938608,0.000003458674,0.000003520062,0.00002817622,0.00001857076,0.0002956555],"genre_scores_gemma":[0.9996556,0.0000258603,0.0002457997,0.000004119005,0.000001650854,0.000002681104,0.00002034637,0.000003685628,0.00004032434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001658705,"threshold_uncertainty_score":0.007523537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008727219542781574,"score_gpt":0.2403247528264092,"score_spread":0.2315975332836276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}