{"id":"W2889882116","doi":"10.1073/pnas.1802320115","title":"Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Medical Research Council; Directorate for Biological Sciences; Research Councils UK; Wellcome Trust; University of Manchester; Kennedy Memorial Trust; Biotechnology and Biological Sciences Research Council; Kennedy Trust for Rheumatology Research","keywords":"Amphiregulin; Immune system; Immunology; Periodontitis; Oral lichen planus; Homeostasis; T cell; Biology; Medicine; Receptor; Cell biology; Epidermal growth factor receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001643207,0.0001404998,0.0002686878,0.0001812426,0.0007011719,0.00002186161,0.0007815669,0.0001732856,0.0000391878],"category_scores_gemma":[0.0009103253,0.00009781327,0.0001425571,0.0005344474,0.001774084,0.0004065772,0.0001799091,0.0001700144,0.00001565561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003578795,"about_ca_system_score_gemma":0.00005893171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009694578,"about_ca_topic_score_gemma":2.507383e-7,"domain_scores_codex":[0.9986904,0.00001152343,0.0003921619,0.0003630342,0.0002305488,0.0003123834],"domain_scores_gemma":[0.9987068,0.0001378766,0.0005287884,0.00001679892,0.0005918111,0.00001790408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006302143,0.00003135184,0.0008352149,0.000052312,0.00005030803,2.722498e-9,0.0006337137,0.00000347769,0.9884091,0.006592458,0.002616807,0.0007122137],"study_design_scores_gemma":[0.0003851255,0.0001305508,0.009355498,0.0001026014,0.00002907144,0.000009935043,0.0007746249,0.00001963509,0.9749836,0.008675516,0.005408799,0.0001250665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945974,0.0004407399,0.000008008027,0.001080562,0.0002787839,0.000309534,0.0006469101,0.00002404311,0.002614036],"genre_scores_gemma":[0.9978722,0.0000288387,0.001023663,0.0001790801,0.0001794467,0.0000137824,0.000001145847,0.000007451211,0.0006944231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01342554,"threshold_uncertainty_score":0.6536687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03926150199120118,"score_gpt":0.2881483665947077,"score_spread":0.2488868646035065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}