{"id":"W2889970702","doi":"10.1101/415554","title":"The Central Nervious System Acts as a Transducer of Stress-Induced Masculinization through Corticotropin-Releasing Hormone B","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Oryzias; Internal medicine; Endocrinology; Sex reversal; Biology; Colocalization; Gonad; Sexual differentiation; Receptor; Mutant; Hormone; Stressor; Cell biology; Gene; Neuroscience; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008177993,0.0003869005,0.0002437482,0.0001945375,0.0002136519,0.0002831319,0.0001651198,0.0002172279,0.00216429],"category_scores_gemma":[0.00007062728,0.0001370545,0.0002450001,0.00005991889,0.0003484137,0.0001694263,0.0003088744,0.000498578,0.0002395455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002727859,"about_ca_system_score_gemma":0.0001925941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00109007,"about_ca_topic_score_gemma":0.001878448,"domain_scores_codex":[0.9998882,0.00001267365,0.000006926864,0.00004155845,0.00002488609,0.00002576289],"domain_scores_gemma":[0.9999017,0.00000567869,0.00003053729,0.000008132858,0.00001268221,0.00004132326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007782926,0.000007096406,0.000334455,0.00003223499,0.000006689913,0.00007902881,0.000009508447,0.00001379799,0.9983894,0.00007720614,0.00004585113,0.0009270437],"study_design_scores_gemma":[0.000071919,0.001012794,0.1374753,0.00004485421,0.00009697484,0.001286067,0.0002855636,0.001166942,0.8490723,0.0002415464,0.00920969,0.00003609716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872823,0.003948479,0.004114301,0.0002286487,0.0001519357,0.00004144815,0.0005842915,0.0002143523,0.003434293],"genre_scores_gemma":[0.9904922,0.001241629,0.002091026,0.0001456751,0.00002521541,0.00003643503,0.0003255742,0.00002601998,0.005616136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00216429,"threshold_uncertainty_score":0.007240295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241453186218427,"score_gpt":0.2360836373509096,"score_spread":0.2236691054887253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}