{"id":"W2890031944","doi":"10.1113/jp276245","title":"Novel mechanisms regulating endothelial barrier function in the pulmonary microcirculation","year":2018,"lang":"en","type":"review","venue":"The Journal of Physiology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Deutsche Forschungsgemeinschaft","keywords":"Barrier function; Interstitial space; Vascular permeability; Paracellular transport; Microcirculation; Transcellular; Cell biology; Lung; Endothelium; Endothelial stem cell; Homeostasis; Chemistry; Permeability (electromagnetism); Medicine; Biology; Pathology; Internal medicine; Biochemistry; In vitro; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003829284,0.0005123295,0.000746947,0.001276618,0.0003191345,0.0009959238,0.000593038,0.0009716775,0.002361954],"category_scores_gemma":[0.000367671,0.0001497776,0.0002617792,0.001007065,0.0004638689,0.001406761,0.0006410558,0.001470395,0.001274056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004085252,"about_ca_system_score_gemma":0.001045813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003880813,"about_ca_topic_score_gemma":0.0005981982,"domain_scores_codex":[0.9999087,0.00001307518,0.00001352099,0.00001985041,0.00003149972,0.00001348424],"domain_scores_gemma":[0.9998611,0.00004860485,0.0000218593,0.000005632358,0.00004131745,0.00002139851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007856698,0.00006325974,0.0002740129,0.01336582,0.00005860917,0.0007012379,0.0001367573,0.0004097396,0.01417575,0.01548725,0.0149342,0.9403148],"study_design_scores_gemma":[0.00001151765,0.000126871,0.001128477,0.002194133,0.00009261185,0.002893204,0.0001314195,0.0001594238,0.004040325,0.005580697,0.9836103,0.00003094299],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004332801,0.9966119,0.0006637144,0.000465094,0.0002682703,0.000006644917,0.0000276099,0.00001494158,0.001508439],"genre_scores_gemma":[0.001899183,0.9965932,0.0004964734,0.0001282911,0.0001667657,0.000008649013,0.00003464627,0.000001680015,0.0006710484],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002361954,"threshold_uncertainty_score":0.007901549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0263323566666424,"score_gpt":0.2789508232349669,"score_spread":0.2526184665683245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}