{"id":"W2890107400","doi":"10.1146/annurev-genet-120417-031321","title":"Phage-Encoded Anti-CRISPR Defenses","year":2018,"lang":"en","type":"review","venue":"Annual Review of Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Arms race; Trans-activating crRNA; Bacteria; Computational biology; CRISPR interference; Genetics; Immune system; Gene; Cas9","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003794743,0.0006955934,0.0008582274,0.001664252,0.0003032025,0.001258503,0.0007318531,0.00106354,0.004709099],"category_scores_gemma":[0.0005386624,0.0002011478,0.0003399252,0.001251868,0.0005467057,0.001028596,0.0006550848,0.001307674,0.003452688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006666788,"about_ca_system_score_gemma":0.0009997826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005605908,"about_ca_topic_score_gemma":0.0007520889,"domain_scores_codex":[0.9997935,0.00002471747,0.00001912829,0.00004509018,0.00009297419,0.0000247281],"domain_scores_gemma":[0.9998037,0.00006875259,0.00002987543,0.000009911327,0.00005999814,0.00002775875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003977148,0.00004771389,0.0002283541,0.01054646,0.00004503597,0.0002787966,0.00007436131,0.0003700568,0.01110368,0.01588444,0.03662602,0.9247553],"study_design_scores_gemma":[0.000003297418,0.00002822106,0.0003235896,0.0009596035,0.00001969755,0.0008446412,0.00002801376,0.00005373543,0.001809404,0.001910097,0.9940081,0.00001164018],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004930866,0.9900096,0.0009630222,0.0008006407,0.0005901263,0.000009128552,0.00006227069,0.00005794323,0.007014226],"genre_scores_gemma":[0.003376402,0.9915697,0.0006535216,0.0004909349,0.0002718903,0.00001328142,0.00009472312,0.000008667593,0.003520915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004709099,"threshold_uncertainty_score":0.01575351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01985452374920558,"score_gpt":0.389898921542253,"score_spread":0.3700443977930474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}