{"id":"W2890107400","doi":"10.1146/annurev-genet-120417-031321","title":"Phage-Encoded Anti-CRISPR Defenses","year":2018,"lang":"en","type":"review","venue":"Annual Review of Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Arms race; Trans-activating crRNA; Bacteria; Computational biology; CRISPR interference; Genetics; Immune system; Gene; Cas9","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004080355,0.0005968275,0.001778028,0.00009051539,0.0000467985,0.0000129144,0.0006825788,0.0004105475,0.00005938402],"category_scores_gemma":[0.000284264,0.000510864,0.0009006207,0.0002729772,0.0001522596,0.000002252235,0.0003360892,0.0001907401,0.00008425831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001386542,"about_ca_system_score_gemma":0.0002855574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002248635,"about_ca_topic_score_gemma":0.000002025816,"domain_scores_codex":[0.9973935,0.0001533669,0.001117584,0.0006369546,0.000286954,0.0004116413],"domain_scores_gemma":[0.9978627,0.0000346039,0.0004802723,0.001122218,0.000350342,0.0001498819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002357813,0.00006544457,0.000003242681,0.1839457,0.0003358998,0.000006462325,0.00001726727,0.000002554666,0.0001505034,0.000009284817,0.0492901,0.7661712],"study_design_scores_gemma":[0.00008877706,0.0002545416,0.000002829458,0.04203511,0.0009205147,0.00006719436,0.000006977556,9.977999e-7,0.001909385,0.000003590251,0.9542267,0.0004833527],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001768307,0.9966335,0.0009882384,0.00001323328,0.0004149204,0.0007564825,0.0003485095,0.00001572234,0.0008116688],"genre_scores_gemma":[0.00001889129,0.9961643,0.001724574,0.0002754488,0.0007068121,0.0000508762,0.0005208192,0.0001111744,0.0004271181],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9049366,"threshold_uncertainty_score":0.9997343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01985452374920558,"score_gpt":0.389898921542253,"score_spread":0.3700443977930474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}