{"id":"W2890115379","doi":"10.3390/vaccines6040066","title":"Virus-Like Particles Are a Superior Platform for Presenting M2e Epitopes to Prime Humoral and Cellular Immunity against Influenza Virus","year":2018,"lang":"en","type":"article","venue":"Vaccines","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Foundation for the National Institutes of Health","keywords":"Virology; Virus; Epitope; Humoral immunity; Prime (order theory); Cellular immunity; Immunity; Biology; Antibody; Immunology; Immune system; Mathematics; Combinatorics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005123658,0.0003251491,0.000580121,0.0002391559,0.0006733176,0.0001209427,0.0002192737,0.0001088489,0.00006078876],"category_scores_gemma":[0.001209308,0.000261179,0.0001183272,0.0003405103,0.0001561188,0.0003212552,0.0005019149,0.0002196854,0.00009918997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006993323,"about_ca_system_score_gemma":0.00008375187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004761812,"about_ca_topic_score_gemma":0.0005884275,"domain_scores_codex":[0.9978543,0.00005063383,0.0004906745,0.00044972,0.000344505,0.0008101725],"domain_scores_gemma":[0.9982202,0.0002323934,0.0001167724,0.0005388765,0.0005741445,0.0003175892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00262085,0.0002739575,0.13387,0.0004830995,0.0003686513,0.0000419203,0.005197495,0.000005876106,0.8396274,0.00007639118,0.00414459,0.0132898],"study_design_scores_gemma":[0.003506246,0.0008818694,0.1848589,0.0002700241,0.0001248605,0.00001046507,0.002101938,0.0005576203,0.7169648,0.000179757,0.09008183,0.0004617307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955916,0.001794038,0.00004279551,0.0004797143,0.0001631377,0.001479129,0.00006909884,0.0001507317,0.000229732],"genre_scores_gemma":[0.9945821,0.0001200287,0.001911083,0.002028639,0.0007080638,0.0002670318,0.00001191763,0.0000641622,0.0003069986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1226626,"threshold_uncertainty_score":0.999984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0943726662303537,"score_gpt":0.3653340559217393,"score_spread":0.2709613896913856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}