{"id":"W2890115379","doi":"10.3390/vaccines6040066","title":"Virus-Like Particles Are a Superior Platform for Presenting M2e Epitopes to Prime Humoral and Cellular Immunity against Influenza Virus","year":2018,"lang":"en","type":"article","venue":"Vaccines","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Foundation for the National Institutes of Health","keywords":"Virology; Virus; Epitope; Humoral immunity; Prime (order theory); Cellular immunity; Immunity; Biology; Antibody; Immunology; Immune system; Mathematics; Combinatorics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002531001,0.0002783609,0.0001627285,0.0001390702,0.000102022,0.0002385822,0.0001412892,0.000448885,0.0007360851],"category_scores_gemma":[0.0001344758,0.0001249288,0.0001544946,0.00005428155,0.000140666,0.0002817653,0.0001882234,0.0003116998,0.0001960159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001055873,"about_ca_system_score_gemma":0.00008370499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001339465,"about_ca_topic_score_gemma":0.0001542339,"domain_scores_codex":[0.9998643,0.00004507858,0.000007700644,0.00002227291,0.00003171559,0.00002882686],"domain_scores_gemma":[0.9999557,0.00001025014,0.00001212239,0.00000512855,0.000006165728,0.00001063914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009844244,0.00005982503,0.0002149744,0.00003212196,0.000005304682,0.00003259757,0.000009382614,0.00006094147,0.9980931,0.00007877513,0.00002433131,0.001290291],"study_design_scores_gemma":[0.00006619037,0.003880063,0.005920064,0.00001255469,0.00002591469,0.0006500926,0.00003988767,0.0009573214,0.9848466,0.0001159197,0.003478759,0.000006556185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995701,0.001356874,0.002072838,0.00004788331,0.0000298337,0.0000299449,0.0000390012,0.00001998294,0.0007027227],"genre_scores_gemma":[0.9966133,0.0003618722,0.002222105,0.00003923838,0.00001275764,0.00001494208,0.0001007338,0.000004482627,0.0006305111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007360851,"threshold_uncertainty_score":0.002462447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0943726662303537,"score_gpt":0.3653340559217393,"score_spread":0.2709613896913856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}