{"id":"W2890238453","doi":"10.1002/sctm.18-0087","title":"Concise Review: Molecular Cytogenetics and Quality Control: Clinical Guardians for Pluripotent Stem Cells","year":2018,"lang":"en","type":"review","venue":"Stem Cells Translational Medicine","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Reprogramming; Induced pluripotent stem cell; Biology; Epigenetics; Epigenome; Genetics; Stem cell; Embryonic stem cell; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003507025,0.001577219,0.002645646,0.002284889,0.0005440519,0.003217164,0.002929958,0.005317804,0.007192875],"category_scores_gemma":[0.008639995,0.0005082655,0.0009322499,0.002638751,0.001856625,0.004037073,0.001715105,0.006804476,0.005573082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001814078,"about_ca_system_score_gemma":0.003095624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009246,"about_ca_topic_score_gemma":0.001359629,"domain_scores_codex":[0.9978094,0.0005731955,0.0004224214,0.0003085466,0.0007556259,0.0001308807],"domain_scores_gemma":[0.9928959,0.002940284,0.0008427734,0.0002239788,0.002471002,0.0006260273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009839525,0.00003178521,0.0001118016,0.01109877,0.0000917351,0.0003220993,0.00005950707,0.0001775589,0.0007134379,0.003046155,0.6354003,0.3488485],"study_design_scores_gemma":[0.00002164291,0.00004347419,0.0002346835,0.002680102,0.00005702559,0.000784136,0.00003535205,0.00004772147,0.0001830868,0.00174426,0.994145,0.00002358888],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008681023,0.946722,0.0007937108,0.01724635,0.03292864,0.00004308683,0.00007437341,0.00005451508,0.002050442],"genre_scores_gemma":[0.0007494923,0.9388072,0.0008110774,0.01719642,0.03894578,0.00007478394,0.0002522064,0.00002711376,0.00313588],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007192875,"threshold_uncertainty_score":0.02406257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1066072605442831,"score_gpt":0.4103329500350553,"score_spread":0.3037256894907722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}