{"id":"W2890292288","doi":"10.3390/vaccines6040067","title":"Catestatin Regulates Epithelial Cell Dynamics to Improve Intestinal Inflammation","year":2018,"lang":"en","type":"article","venue":"Vaccines","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"STAT3; STAT protein; Colitis; Inflammation; Ulcerative colitis; Intestinal mucosa; Intestinal epithelium; Immune system; Interleukin; Immunology; Chemistry; Medicine; Cancer research; Phosphorylation; Internal medicine; Biology; Cell biology; Epithelium; Pathology; Cytokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001102342,0.0001509553,0.00008159901,0.00005276051,0.0000805403,0.0000323354,0.0001706246,0.0000773559,0.00004251803],"category_scores_gemma":[0.0001908242,0.0001437134,0.00004410039,0.00007778416,0.00002796231,0.000006115893,0.0001143317,0.00004086947,0.0002005507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002178656,"about_ca_system_score_gemma":0.00006687954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000227273,"about_ca_topic_score_gemma":0.0002972853,"domain_scores_codex":[0.9991811,0.00003209487,0.0002000127,0.0002885557,0.00007983545,0.000218416],"domain_scores_gemma":[0.9992329,0.000008983094,0.00007817351,0.0003236017,0.0002443393,0.0001119841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003811876,0.00002392258,0.008794612,0.00003400113,0.00001065992,0.0000108514,0.00007716413,0.00004972893,0.9839978,0.0001088847,0.001469646,0.005041542],"study_design_scores_gemma":[0.0005950111,0.000383363,0.09056417,0.00001607174,0.0000211968,0.000008463479,0.00006901474,0.002362321,0.9008199,0.0002181303,0.004638366,0.0003039966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996897,0.0000130767,0.001227536,0.0001901695,0.0002298333,0.0002318442,0.00003579955,0.00003393157,0.001140803],"genre_scores_gemma":[0.9943614,0.000003155286,0.002730078,0.0001441478,0.001076925,0.00003086633,0.0001363524,0.00002899073,0.001488074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08317791,"threshold_uncertainty_score":0.5860464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00386625700726616,"score_gpt":0.2218567406908077,"score_spread":0.2179904836835415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}