{"id":"W2890292288","doi":"10.3390/vaccines6040067","title":"Catestatin Regulates Epithelial Cell Dynamics to Improve Intestinal Inflammation","year":2018,"lang":"en","type":"article","venue":"Vaccines","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"STAT3; STAT protein; Colitis; Inflammation; Ulcerative colitis; Intestinal mucosa; Intestinal epithelium; Immune system; Interleukin; Immunology; Chemistry; Medicine; Cancer research; Phosphorylation; Internal medicine; Biology; Cell biology; Epithelium; Pathology; Cytokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001229823,0.0002769896,0.0004533168,0.000250234,0.0001332028,0.0003326604,0.0001898872,0.0003711977,0.001573544],"category_scores_gemma":[0.00008480894,0.00009462616,0.0003391755,0.000192568,0.0001903242,0.0002827206,0.0002466906,0.0008334781,0.0003222208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001776672,"about_ca_system_score_gemma":0.0001985489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002635814,"about_ca_topic_score_gemma":0.0006253282,"domain_scores_codex":[0.9998841,0.00002306636,0.00001202944,0.00002459925,0.00002707423,0.00002905292],"domain_scores_gemma":[0.9999421,0.000005573288,0.00001734145,0.000006364178,0.00001133101,0.00001738563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000658623,0.0003236992,0.000619959,0.0003674914,0.00002651687,0.00008266842,0.00003661573,0.0001479551,0.9851634,0.0002007537,0.0002902008,0.01208213],"study_design_scores_gemma":[0.0002267012,0.003135142,0.0202897,0.0000504306,0.0001612682,0.0005594288,0.00009810662,0.001573166,0.952803,0.0001976223,0.02088843,0.00001699698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697981,0.02091734,0.004961207,0.0005577381,0.0001971891,0.00009835567,0.0003882878,0.0003704955,0.002711267],"genre_scores_gemma":[0.9862658,0.006321923,0.003203836,0.0002317197,0.00003537581,0.00005557546,0.0005003834,0.00003121827,0.003354057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001573544,"threshold_uncertainty_score":0.005263984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00386625700726616,"score_gpt":0.2218567406908077,"score_spread":0.2179904836835415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}