{"id":"W2890401619","doi":"10.1101/415794","title":"Bacterial outer membrane vesicles provide an alternative pathway for trafficking of type III secreted effectors into epithelial cells","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; National Institutes of Health","keywords":"Effector; Intimin; Secretion; Type three secretion system; Biology; Bacterial outer membrane; Cell biology; Vesicle; Microbiology; Virulence; Escherichia coli; Enterobacteriaceae; Biochemistry; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001398541,0.0002918538,0.0002350713,0.0001181736,0.0001680468,0.0007075617,0.0002083484,0.0004401164,0.001037755],"category_scores_gemma":[0.0001352157,0.0001251214,0.0004911419,0.00008517106,0.0001481407,0.0003708994,0.0004762232,0.000612651,0.0008344412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003179077,"about_ca_system_score_gemma":0.0002023763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002715421,"about_ca_topic_score_gemma":0.000250099,"domain_scores_codex":[0.9998617,0.00002665475,0.000009594813,0.00002374544,0.00003828793,0.00004003943],"domain_scores_gemma":[0.9998436,0.00002872226,0.00002567093,0.0000352388,0.00004024977,0.00002647215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006342785,0.000007715415,0.0002734261,0.00003368165,0.000004613566,0.00008562103,0.00001618204,0.00002834449,0.9983639,0.0002716374,0.00002957,0.0008218525],"study_design_scores_gemma":[0.0000111134,0.0001624186,0.005174557,0.0000195523,0.00001318873,0.0005899493,0.0001204147,0.00167043,0.9869965,0.0001919754,0.005040176,0.000009690111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748241,0.001900787,0.02027113,0.0002074207,0.0001100209,0.00003920334,0.0004097382,0.0001629386,0.002074627],"genre_scores_gemma":[0.9899344,0.0005175791,0.00507213,0.00006469513,0.000008462354,0.00002365857,0.0004722955,0.00003442548,0.003872415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001037755,"threshold_uncertainty_score":0.003471613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01438899156373462,"score_gpt":0.2527596261686759,"score_spread":0.2383706346049413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}