{"id":"W2890422552","doi":"10.1210/jc.2018-00544","title":"The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome","year":2018,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Ovarian function and disorders","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institutes of Health; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Shandong University","keywords":"Polycystic ovary; HMGA2; Gene knockdown; Granulosa cell; Biology; Cell growth; Endocrinology; Messenger RNA; Internal medicine; Ovary; Cell culture; Gene; Medicine; Genetics; microRNA; Insulin resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001113243,0.0002473199,0.0001830792,0.0003982401,0.0001586085,0.000188809,0.00009770068,0.0002122856,0.001130846],"category_scores_gemma":[0.0002905797,0.0001050999,0.0002153778,0.0002495378,0.0002330388,0.00007948352,0.000203643,0.0002114888,0.000100631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001913525,"about_ca_system_score_gemma":0.0001723575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000632528,"about_ca_topic_score_gemma":0.0008203967,"domain_scores_codex":[0.9999291,0.00001984351,0.000005767015,0.00001639694,0.00001777667,0.00001117814],"domain_scores_gemma":[0.9999187,0.00001565982,0.00003193936,0.000006698755,0.000006734305,0.00002034191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00403411,0.0001090413,0.2910362,0.0005104534,0.0002983207,0.004102605,0.0002208547,0.0004040137,0.6777546,0.0003198623,0.0007347857,0.0204751],"study_design_scores_gemma":[0.0001625213,0.0003785232,0.9295967,0.00003865324,0.0001507818,0.005773122,0.0001850064,0.001216597,0.05992015,0.0003629788,0.002203512,0.00001158369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948244,0.003495535,0.0006630438,0.0001617823,0.0000235054,0.00001374228,0.0002904848,0.00004264094,0.0004849524],"genre_scores_gemma":[0.9984579,0.0006671164,0.0003969638,0.00005020886,0.00001533555,0.00001259679,0.0001774829,0.000003277631,0.0002191007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001130846,"threshold_uncertainty_score":0.003783047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03445562040443764,"score_gpt":0.3339919656984175,"score_spread":0.2995363452939799,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}