{"id":"W2890440333","doi":"10.1093/dote/doy089.ps02.153","title":"PS02.153: HER2 PATHWAY CONTROL SENSITIVITY TO CISPLATIN IN ESOPHAGEAL ADENOCARCINOMA CELL LINES","year":2018,"lang":"en","type":"article","venue":"Diseases of the Esophagus","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Cisplatin; Medicine; Cancer research; Adenocarcinoma; Cell culture; Esophageal cancer; Chemotherapy; Downregulation and upregulation; Cell growth; Oncology; Cancer; Esophagus; Cell; Internal medicine; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002204442,0.0002773193,0.000408599,0.0002700092,0.0002724893,0.0003575861,0.0003030647,0.0004073428,0.003741851],"category_scores_gemma":[0.0001708734,0.0001885844,0.0003237428,0.0004818975,0.0002059469,0.000243735,0.0001916784,0.0006160294,0.001124715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003905586,"about_ca_system_score_gemma":0.0003734006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001937064,"about_ca_topic_score_gemma":0.001915364,"domain_scores_codex":[0.9996792,0.00004932867,0.00004498959,0.0000661277,0.0001125872,0.00004768094],"domain_scores_gemma":[0.9999102,0.00001520057,0.00001422964,0.00002163431,0.00002312414,0.0000155633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002124778,0.000157331,0.000564701,0.00006510074,0.00001222506,0.00009926433,0.00003891594,0.0001991925,0.9958445,0.0001487556,0.0006214377,0.002036141],"study_design_scores_gemma":[0.0000874813,0.001099749,0.01367227,0.00001043006,0.00004906194,0.000797802,0.0001138636,0.00312069,0.9700926,0.00008091068,0.010861,0.00001425765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985953,0.001905513,0.003348038,0.0002926443,0.0001158749,0.0001369518,0.003933305,0.0001835899,0.004131132],"genre_scores_gemma":[0.9763125,0.001313959,0.003369225,0.000176982,0.00001400433,0.0003648232,0.006526501,0.00004419169,0.01187778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003741851,"threshold_uncertainty_score":0.01251775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425042450745893,"score_gpt":0.2992810073715946,"score_spread":0.2850305828641356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}