{"id":"W2890476709","doi":"10.1101/424499","title":"Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Center for Cellular Imaging, Washington University; Otsuka Canada Pharmaceutical","keywords":"Circadian rhythm; Dopaminergic; Morning; Evening; Neuroscience; Biological neural network; Biology; Dopamine; Internal medicine; Endocrinology; Medicine; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007385301,0.0001474656,0.0001671743,0.000138646,0.0001800998,0.0003308182,0.0002112248,0.0002263571,0.001442882],"category_scores_gemma":[0.0001155674,0.0001190159,0.0001572811,0.00005331182,0.0002234078,0.0002168596,0.0003767982,0.000435761,0.0003097039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002849441,"about_ca_system_score_gemma":0.000210698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006550617,"about_ca_topic_score_gemma":0.001784452,"domain_scores_codex":[0.9999344,0.000005166309,0.000004536681,0.0000220785,0.00001664403,0.00001705912],"domain_scores_gemma":[0.9999028,0.000008604763,0.00002991814,0.0000140233,0.00001242702,0.00003219957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001098835,0.00001061335,0.001476665,0.00001953807,0.000004445373,0.00005158575,0.00002935662,0.00006119583,0.9942201,0.0009171783,0.00008284827,0.003016505],"study_design_scores_gemma":[0.00004609893,0.0002263979,0.1027591,0.00002709386,0.00001768293,0.0003540052,0.00009845249,0.002361792,0.8863993,0.0007627765,0.006933287,0.00001408115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827033,0.0008356817,0.01055374,0.0001463041,0.00004282443,0.00001868124,0.0002882043,0.0001864644,0.005224667],"genre_scores_gemma":[0.9906576,0.0001812467,0.003878958,0.00006015492,0.00001199791,0.0000153735,0.0001740629,0.00002986357,0.004990739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001442882,"threshold_uncertainty_score":0.004826903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01641677861860116,"score_gpt":0.2161688922542516,"score_spread":0.1997521136356504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}