{"id":"W2890491110","doi":"10.1007/s11010-018-3444-3","title":"The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1","year":2018,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; Biology; Wallerian degeneration; Apoptosis; Signal transducing adaptor protein; Cytosol; Signal transduction; Neuroscience; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009736371,0.000334551,0.0001857456,0.00001438954,0.0004527406,0.000143109,0.000366756,0.0002735753,0.00003713641],"category_scores_gemma":[0.0001163032,0.0002658342,0.0002011523,0.0001021812,0.0006720576,0.000006058382,0.0002673825,0.0001426164,0.00002725274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000159643,"about_ca_system_score_gemma":0.00008925005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003161195,"about_ca_topic_score_gemma":0.000003062599,"domain_scores_codex":[0.9981675,0.00007064456,0.0002788812,0.0006728289,0.0002652437,0.0005449324],"domain_scores_gemma":[0.9987267,0.0000180084,0.0001035275,0.0007814685,0.0001408016,0.0002294512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001705825,0.00005145307,0.0001445875,0.00003391879,0.00009277555,0.000005534338,0.000026199,0.000001353929,0.9903864,0.0002279716,0.008275156,0.000584049],"study_design_scores_gemma":[0.0006549605,0.0001331331,0.000004999531,0.00001933605,0.00005496949,0.00001110025,0.000205821,0.00001769582,0.9525555,0.0002777237,0.04572032,0.0003444876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849358,0.0049723,0.004034489,0.0004459376,0.0005455073,0.0001995275,0.00005300184,0.0000305039,0.00478295],"genre_scores_gemma":[0.995519,0.0002700226,0.0009872217,0.0005580973,0.0007727568,0.0000527624,0.0002662891,0.00004675776,0.001527092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03783096,"threshold_uncertainty_score":0.9999794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004817062534587785,"score_gpt":0.2180294703593785,"score_spread":0.2132124078247907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}