{"id":"W2890496731","doi":"10.1200/jco.2017.35.15_suppl.8015","title":"Pembrolizumab (Pembro) plus lenalidomide (Len) and low-dose dexamethasone (Dex) for relapsed/refractory multiple myeloma (RRMM): Efficacy and biomarker analyses.","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Lenalidomide; Neutropenia; Internal medicine; Pembrolizumab; Multiple myeloma; Oncology; Toxicity; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001158801,0.0004820546,0.0008845781,0.0003845237,0.0001689655,0.0004851103,0.0005178201,0.0004352549,0.001448491],"category_scores_gemma":[0.0004360425,0.0002814898,0.0004620904,0.0003984453,0.0002920751,0.0004758142,0.0002356217,0.0008622988,0.0004120091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007895808,"about_ca_system_score_gemma":0.0005790099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005987247,"about_ca_topic_score_gemma":0.002549035,"domain_scores_codex":[0.9997573,0.00009489463,0.00002073028,0.00004679203,0.00004424856,0.00003599486],"domain_scores_gemma":[0.9997789,0.00004406624,0.00007326503,0.00001534468,0.00001141289,0.00007690721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3182411,0.02470131,0.06357249,0.001535962,0.002127367,0.0007030399,0.0002876912,0.003256154,0.1010763,0.0003207554,0.003706336,0.4804714],"study_design_scores_gemma":[0.1045409,0.5893047,0.2616915,0.0002338968,0.002579068,0.002512507,0.000178909,0.003639544,0.01975253,0.0002751188,0.01523757,0.00005393332],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989003,0.008271012,0.000275943,0.0002081549,0.00002657538,0.0004384617,0.0005020371,0.00004111665,0.001233712],"genre_scores_gemma":[0.9952915,0.002013457,0.0006891413,0.0002607172,0.00005126272,0.0002034988,0.0008060191,0.000005976106,0.000678455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001448491,"threshold_uncertainty_score":0.00612843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2901557358574638,"score_gpt":0.5321339181034322,"score_spread":0.2419781822459684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}