{"id":"W2890598685","doi":"10.1016/j.neo.2018.08.007","title":"Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma","year":2018,"lang":"en","type":"article","venue":"Neoplasia","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Notch signaling pathway; Neural stem cell; Gene knockdown; Neurosphere; Stem cell; Biology; Chromatin immunoprecipitation; Nestin; Cancer research; Transcription factor; Cell biology; Molecular biology; Cellular differentiation; Chemistry; Cell culture; Signal transduction; Gene expression; Adult stem cell; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006647315,0.000106934,0.00007897721,0.00002686307,0.00006605767,0.00002710977,0.0001824456,0.0001069825,0.0001729517],"category_scores_gemma":[0.0001104979,0.00008141792,0.00005108969,0.00009318681,0.0001016168,0.000003497104,0.00008977961,0.00005916569,0.0001890601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001542609,"about_ca_system_score_gemma":0.00003133659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001871427,"about_ca_topic_score_gemma":0.0001601819,"domain_scores_codex":[0.9992867,0.00006542904,0.0001212181,0.000257527,0.0000943847,0.0001747147],"domain_scores_gemma":[0.9994262,0.00001800488,0.00004803128,0.0004177363,0.00004595665,0.00004410525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001750054,0.00003159744,0.004992281,0.00001196976,0.00001697858,0.000002888944,0.0001159995,0.000007125324,0.9859392,0.00002626218,0.00703676,0.001643898],"study_design_scores_gemma":[0.0004878313,0.0003055931,0.1241468,0.00002282386,0.000009773597,0.00002096889,0.0000328338,0.0001354142,0.7688441,0.00002818347,0.1057998,0.0001658248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985843,0.0001570413,0.00003573665,0.0001474161,0.0001691982,0.0001854573,0.00001416973,0.00001768919,0.0006890501],"genre_scores_gemma":[0.9991435,0.00001184104,0.00006830369,0.0001776592,0.0004045667,0.00001092374,0.00001090737,0.00002256641,0.0001496765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2170951,"threshold_uncertainty_score":0.3320127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0059778914460958,"score_gpt":0.2397537662413102,"score_spread":0.2337758747952144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}