{"id":"W2890945106","doi":"10.1089/dna.2018.4362","title":"Cardiac <i>Fgf-16</i> Expression Supports Cardiomyocyte Survival and Increases Resistance to Doxorubicin Cytotoxicity","year":2018,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Applied Materials","keywords":"Gene knockdown; Biology; Doxorubicin; Context (archaeology); Cardiac function curve; Fibroblast growth factor; Endocrinology; Internal medicine; Pharmacology; Heart failure; Chemotherapy; Medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002914459,0.000198605,0.0002734493,0.00005790084,0.0001489496,0.0000248526,0.0001400185,0.0002257932,0.00002694483],"category_scores_gemma":[0.00007333136,0.0001720293,0.00005827793,0.00008580423,0.0003413231,0.000004898582,0.0003956145,0.00009302174,0.0000139426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001396323,"about_ca_system_score_gemma":0.00004939574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001294793,"about_ca_topic_score_gemma":0.0001329621,"domain_scores_codex":[0.9984487,0.0002433566,0.0001725306,0.0006106878,0.0000978141,0.0004268554],"domain_scores_gemma":[0.9992076,0.00004332531,0.00004560914,0.0003651018,0.00008739768,0.000250933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000311853,0.00002021948,0.02261296,0.00003012583,0.00002427892,0.000003316224,0.00003248922,8.520259e-8,0.9725097,0.00003363119,0.004156497,0.0002648596],"study_design_scores_gemma":[0.000304804,0.0004894427,0.007133902,0.00001338604,0.000009027267,0.000003362511,0.00006175337,4.176761e-7,0.8958011,0.00005088904,0.0959347,0.0001972484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992376,0.001210151,0.0001394975,0.00007148424,0.0001622916,0.000237968,0.0001239781,0.00001586507,0.00566281],"genre_scores_gemma":[0.9980402,0.0003138292,0.0001813088,0.0001520469,0.0004207926,0.00002417529,0.0001282024,0.00002090566,0.0007185324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0917782,"threshold_uncertainty_score":0.701515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007585991397796543,"score_gpt":0.2493751520855306,"score_spread":0.2417891606877341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}