{"id":"W2890977830","doi":"10.3324/haematol.2018.194282","title":"Daratumumab plus lenalidomide and dexamethasone <i>versus</i> lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX","year":2018,"lang":"en","type":"article","venue":"Haematologica","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; University of Calgary; University of British Columbia; University of Alberta; Queen Elizabeth II Health Sciences Centre; Université Laval; Dalhousie University","funders":"Raymond and Beverly Sackler Institute for Biological, Physical and Engineering Sciences, Yale University; Yale University","keywords":"Lenalidomide; Daratumumab; Dexamethasone; Medicine; Hazard ratio; Multiple myeloma; Internal medicine; Oncology; Confidence interval; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004667049,0.0006030098,0.00213552,0.0006139363,0.0001678719,0.001113515,0.0007347136,0.0004292815,0.00165926],"category_scores_gemma":[0.003575111,0.0003182385,0.004091956,0.0008394052,0.0002788313,0.0005684486,0.0004454345,0.001126542,0.0001687112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006456976,"about_ca_system_score_gemma":0.0007558254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002367671,"about_ca_topic_score_gemma":0.005380192,"domain_scores_codex":[0.997887,0.00135162,0.0001446808,0.0002116866,0.0002805275,0.0001245648],"domain_scores_gemma":[0.9973569,0.001360412,0.0007244931,0.0002078148,0.000147636,0.0002026509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5945466,0.001019505,0.1045962,0.004556805,0.06261363,0.000288795,0.0001892292,0.003498951,0.003993139,0.000433577,0.004323686,0.2199399],"study_design_scores_gemma":[0.1723603,0.0933557,0.5062202,0.001008893,0.1928898,0.001229655,0.0003001162,0.005021052,0.005528777,0.001214056,0.0206765,0.0001948375],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9312059,0.06198835,0.0008706765,0.0005858658,0.0002758053,0.0002441636,0.002513429,0.00005604362,0.002259749],"genre_scores_gemma":[0.985453,0.01015961,0.0007841694,0.0005368547,0.0002865328,0.0001054003,0.001762823,0.00001881039,0.0008929456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004667049,"threshold_uncertainty_score":0.02468199,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06103873061989124,"score_gpt":0.341154983171765,"score_spread":0.2801162525518738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}