{"id":"W2891044811","doi":"10.1097/olq.0000000000000745","title":"High Baseline Anal Human Papillomavirus and Abnormal Anal Cytology in a Phase 3 Trial of the Quadrivalent Human Papillomavirus Vaccine in Human Immunodeficiency Virus–Infected Individuals Older Than 26 Years: ACTG 5298","year":2017,"lang":"en","type":"article","venue":"Sexually Transmitted Diseases","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; University of California, San Francisco; University of California, San Diego; National Institutes of Health; York University; National Institute of Dental and Craniofacial Research; Weill Cornell Medical College; Georgia Clinical and Translational Science Alliance; National Center for Advancing Translational Sciences; ACT Government; University of Cincinnati; National Cancer Institute; University of Rochester; Gilead Sciences; GlaxoSmithKline; Massachusetts General Hospital; Rush University; Washington University in St. Louis; Northwestern University","keywords":"Medicine; Anal cancer; Men who have sex with men; Cytology; Genotyping; Papillomaviridae; Internal medicine; Gynecology; Human immunodeficiency virus (HIV); Cancer; Genotype; Cervical cancer; Immunology; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001774132,0.001045117,0.001121464,0.0002826281,0.0004725282,0.0008724037,0.0005988211,0.00115782,0.003590571],"category_scores_gemma":[0.001130848,0.0005361363,0.001118317,0.000229651,0.0005441529,0.0006352082,0.0002897799,0.002201171,0.0005157327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004735003,"about_ca_system_score_gemma":0.001145669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086818,"about_ca_topic_score_gemma":0.002137059,"domain_scores_codex":[0.9995753,0.0002159045,0.0000215386,0.00006277375,0.00003784462,0.00008656353],"domain_scores_gemma":[0.9992896,0.0001564474,0.0001366036,0.00004163569,0.00006720425,0.0003084131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9282169,0.02735049,0.007931625,0.0004444482,0.0006460014,0.000146122,0.0002429481,0.0004863389,0.007253987,0.0001133434,0.001311762,0.02585608],"study_design_scores_gemma":[0.6141646,0.3630947,0.01967204,0.00006626151,0.0005145377,0.0001137795,0.0000632945,0.0006444499,0.0006531826,0.00009552801,0.000895869,0.00002155694],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973512,0.0006620641,0.0001085699,0.0001811028,0.00006366674,0.0008802742,0.0002426557,0.0000225714,0.0004879487],"genre_scores_gemma":[0.9948447,0.0006242376,0.0004943262,0.0006398581,0.00009906381,0.001710355,0.0005201017,0.000007844911,0.001059509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003590571,"threshold_uncertainty_score":0.01201171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02695690190910702,"score_gpt":0.3606937296838572,"score_spread":0.3337368277747502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}