{"id":"W2891080835","doi":"10.1016/j.nmd.2018.06.310","title":"SMA THERAPIES II AND BIOMARKERS","year":2018,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"SMA*; Spinal muscular atrophy; Medicine; Supplementary motor area; Neurofilament; Internal medicine; Gastroenterology; Disease; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001548627,0.0002157682,0.0002384399,0.0001825756,0.0003412935,0.00003181055,0.0001279029,0.00008771431,0.0003183779],"category_scores_gemma":[0.0001053701,0.0001855579,0.0001573154,0.0003406287,0.0006743633,0.00005957304,0.0001556861,0.0001738739,0.00005636193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009988515,"about_ca_system_score_gemma":0.00006559976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005165414,"about_ca_topic_score_gemma":0.00005317407,"domain_scores_codex":[0.9983966,0.0000891942,0.0001793519,0.0005022695,0.0004067686,0.000425802],"domain_scores_gemma":[0.9991397,0.00003033527,0.00003383871,0.0004859193,0.00008392648,0.0002263055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009795913,0.001283281,0.1532748,0.0004074483,0.00140719,0.0001272762,0.00313269,0.000001440814,0.1431048,0.001508271,0.01091277,0.6838605],"study_design_scores_gemma":[0.005537988,0.003642451,0.4151646,0.00006292364,0.0002355884,0.0001821578,0.0008297829,0.0005081588,0.004364284,0.001369427,0.5675369,0.000565735],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811076,0.002556629,0.0002332092,0.005351714,0.0001507233,0.0006306291,0.000002450668,0.0001135591,0.009853499],"genre_scores_gemma":[0.9951821,0.002187804,0.0004331999,0.001380079,0.00008860901,0.00003243839,0.000008653346,0.00005916961,0.0006279693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6832947,"threshold_uncertainty_score":0.7566831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01236496653827061,"score_gpt":0.2773766546933382,"score_spread":0.2650116881550676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}