{"id":"W2891080835","doi":"10.1016/j.nmd.2018.06.310","title":"SMA THERAPIES II AND BIOMARKERS","year":2018,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"Neurogenetic and Muscular Disorders Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"SMA*; Spinal muscular atrophy; Medicine; Supplementary motor area; Neurofilament; Internal medicine; Gastroenterology; Disease; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001543584,0.0009113342,0.001105954,0.001917817,0.0004152962,0.003102601,0.0003589787,0.00120896,0.005395808],"category_scores_gemma":[0.002569502,0.0002243353,0.000704119,0.001248579,0.000606904,0.0009655379,0.0007596322,0.001320073,0.001704497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001067009,"about_ca_system_score_gemma":0.001129174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000760567,"about_ca_topic_score_gemma":0.001078862,"domain_scores_codex":[0.9991075,0.0003384714,0.0001097658,0.0001325056,0.000229625,0.00008197142],"domain_scores_gemma":[0.9988598,0.0003724538,0.0003854913,0.00005451342,0.0001899806,0.000137858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003141712,0.0006058232,0.06687795,0.002566865,0.001092208,0.001023069,0.0002241171,0.00093375,0.01473642,0.01742858,0.02932933,0.8620403],"study_design_scores_gemma":[0.000771741,0.007347659,0.2599842,0.008860437,0.002491675,0.007681606,0.000895613,0.002093639,0.02518345,0.04967451,0.6348212,0.0001943106],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.05233396,0.8512454,0.005675843,0.01739455,0.003013212,0.0001382679,0.001349597,0.0001824036,0.06866672],"genre_scores_gemma":[0.5496244,0.3539788,0.01504288,0.01398914,0.008839284,0.0005156614,0.003007601,0.00008592165,0.05491629],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.005395808,"threshold_uncertainty_score":0.01805073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01236496653827061,"score_gpt":0.2773766546933382,"score_spread":0.2650116881550676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}