{"id":"W2891191674","doi":"10.21769/bioprotoc.3005","title":"Selective Isolation of Retroviruses from Extracellular Vesicles by Intact Virion Immunoprecipitation","year":2018,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Immunoprecipitation; Viral envelope; Epitope; Glycoprotein; Nucleic acid; Murine leukemia virus; Biology; Virus; Cell biology; Cell culture; Virology; Vesicle; Virus-like particle; Chemistry; Retrovirus; Molecular biology; Biochemistry; Membrane; Antibody; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002059826,0.0002084824,0.0001622328,0.0000535186,0.0001029035,0.00003149822,0.0002562372,0.0002346001,0.0001413204],"category_scores_gemma":[0.0001724003,0.0002111005,0.0001031401,0.000150865,0.0002215402,0.0000213541,0.00009444948,0.00009036112,0.00005174973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004118071,"about_ca_system_score_gemma":0.00008731361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001011943,"about_ca_topic_score_gemma":0.00001731946,"domain_scores_codex":[0.9985295,0.0001718358,0.0004192721,0.0004509434,0.0002143786,0.0002140627],"domain_scores_gemma":[0.9988244,0.00002589239,0.0003317606,0.0005063324,0.0002343437,0.00007730052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001012748,0.0001929642,0.006038589,0.00002946574,0.00005262987,6.232351e-7,0.00009425107,0.000002674054,0.9838848,0.00003204331,0.005173654,0.003485623],"study_design_scores_gemma":[0.00119507,0.0008891117,0.008371666,0.0000341622,0.00001991737,6.625805e-7,0.00005287268,0.0001514849,0.9565954,0.0003864569,0.03207447,0.0002287154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8081476,0.0001357597,0.012584,0.00002973205,0.0001041615,0.1781103,0.0001330867,0.00004536063,0.0007100427],"genre_scores_gemma":[0.8271452,0.000002211745,0.002835929,0.00004953631,0.0003434652,0.1691692,0.0002304606,0.00004139071,0.000182657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02728932,"threshold_uncertainty_score":0.860843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01038960651679264,"score_gpt":0.2904802689290101,"score_spread":0.2800906624122174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}