{"id":"W2891337611","doi":"10.1200/jco.2017.35.15_suppl.tps3098","title":"A phase I single arm, open label clinical trial evaluating safety of MAGE-A10<sup>c796</sup>T in subjects with advanced or metastatic head and neck, melanoma, or urothelial tumors (NCT02989064).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Context (archaeology); Melanoma; Internal medicine; Cyclophosphamide; Oncology; Head and neck cancer; Immunotherapy; Cancer; Chemotherapy; Urology; Surgery; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001104261,0.001410463,0.001353712,0.0003189277,0.0004436996,0.0007888881,0.0007267087,0.001516441,0.009817982],"category_scores_gemma":[0.0006497533,0.0004011065,0.0006992256,0.0003148729,0.0008196259,0.0008874861,0.0002914628,0.002785149,0.00201492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007566823,"about_ca_system_score_gemma":0.001859538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000666466,"about_ca_topic_score_gemma":0.002089989,"domain_scores_codex":[0.9997306,0.0001100458,0.000009319742,0.00005369697,0.00002740623,0.00006889491],"domain_scores_gemma":[0.9993813,0.00007762313,0.0001345757,0.00004202304,0.00003987124,0.0003244443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8634421,0.06070376,0.00171507,0.0006553755,0.0005213477,0.0001913566,0.0001395028,0.001318529,0.02989364,0.00030853,0.005641246,0.03546958],"study_design_scores_gemma":[0.5381472,0.4528603,0.002890642,0.00002426468,0.0001605531,0.0001414375,0.00004137962,0.0007043913,0.002164045,0.0002849809,0.002565901,0.00001494862],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758246,0.001545493,0.001308879,0.0006931318,0.0003463348,0.0111731,0.003745095,0.0002568573,0.005106566],"genre_scores_gemma":[0.9695734,0.001243311,0.002098723,0.001481407,0.0002491071,0.01215127,0.00382264,0.00005070817,0.009329366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009817982,"threshold_uncertainty_score":0.03284442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2868310845853931,"score_gpt":0.5290232871734059,"score_spread":0.2421922025880127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}